Purpose: This study evaluates the effect of a 10-week psychoeducation program (PP) on disease burden, depression, and anxiety levels in relatives of psychotic patients.Design and Methods: The participants were 43 relatives of patients attending a community mental health center. The Zarit Caregiver Burden Scale (ZCBS), Beck Anxiety Inventory (BAI), and Beck Depression Inventory (BDI) were used to collect psychometric data.Findings: Administering the PP to caregivers significantly reduced their ZCBS, BAI, and BDI scores.Practice Implications: We recommend integrating the PP into treatment and rehabilitation programs within the scope of psychiatric-care services.