Burden of Chronic Respiratory Diseases (CRD) in Middle East and North Africa (MENA)

Abdallah, F Ben; Taktak, S; Chtourou, A; Mahouachi, R; Kheder, A. Ben

doi:10.1097/1939-4551-4-s1-s6

Cited by 11 publications

(23 citation statements)

References 9 publications

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“… 43 Chan-Yeung et al estimate a prevalence of 179 per 100,000 in Africa and 301 per 100,000 in Eastern Mediterranean countries, less than that of America and Europe. 7 , 44 However, a recent systematic analysis by Adeolaye et al reported the estimated median prevalence of COPD in persons aged 40 years or older as 13.4% (range 9·4% to 22·1%), translating into 26.3 million (18.5 to 43.4 million) cases of COPD in SSA. 45 Within the SSA region, Cape Town in South Africa had the highest prevalence estimates published within the international BOLD study, as GOLD stage II prevalence was 22.2% in men above 40 years.…”

Section: Copd and Asthma Disease Burdenmentioning

confidence: 99%

“…Although there is a paucity of good epidemiological data, there appears to be substantial differences in prevalence estimations between countries in the region. 44 , 49 Tunisia reportedly has a prevalence of 3.8% compared to 125 per 100,000 people in Algeria and 5.6% in Lebanon. 44 A recent study from Saudi Arabia estimated COPD prevalence to be 2.4% in the general population and 14.2% among smokers (56).…”

Section: Copd and Asthma Disease Burdenmentioning

confidence: 99%

“… 44 , 49 Tunisia reportedly has a prevalence of 3.8% compared to 125 per 100,000 people in Algeria and 5.6% in Lebanon. 44 A recent study from Saudi Arabia estimated COPD prevalence to be 2.4% in the general population and 14.2% among smokers (56). United Arab Emirates reports a prevalence of 3.7% in 40 to 80 year olds in Abu Dhabi.…”

Section: Copd and Asthma Disease Burdenmentioning

confidence: 99%

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The epidemiology of noncommunicable respiratory disease in sub-Saharan Africa, the Middle East, and North Africa

Ahmed¹,

Robinson

Mortimer

2017

Mal. Med. J

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Noncommunicable diseases (NCDs) are a major and increasing global health issue. The World Health Organization (WHO) estimates that NCDs represent 63% of all global deaths of which 3.9 million are due to chronic respiratory diseases (CRDs) and Chronic Obstructive Pulmonary Disease (COPD) in particular. COPD is now the third most common cause of death globally; 90% of these deaths occur in Low and Middle Income Countries (LMICs). COPD affects 329 million people, almost 5% of the world's population. In addition, asthma affects 334 million people, again representing almost 5% of the world's population. There is limited literature published on the epidemiology of COPD and Asthma from Sub-Saharan Africa (SSA) and Middle East and North Africa (MENA). Both diseases are under-diagnosed and underestimated in both SSA and MENA regions. The burden of COPD in sub-Saharan Africa is disputed and reports offer variable prevalence estimates, ranging from 4.1% to almost 22.2%. SSA and MENA countries report similar mortality rates from COPD of 18 per 100,000 population (2001 data). Asthma is a less common cause of death than COPD but is a major cause of morbidity; WHO estimates that there are 250,000 deaths per year from asthma, mainly in LMICs and it remains in the top twenty causes of disability in children globally. Risk factors for CRD are genetic and environmental; the latter dominated by air pollution exposures including tobacco smoke, household air pollution, outdoor air pollution and occupational exposures.

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Section: Copd and Asthma Disease Burdenmentioning

confidence: 99%

Section: Copd and Asthma Disease Burdenmentioning

confidence: 99%

Section: Copd and Asthma Disease Burdenmentioning

confidence: 99%

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The epidemiology of noncommunicable respiratory disease in sub-Saharan Africa, the Middle East, and North Africa

Ahmed¹,

Robinson

Mortimer

2017

Mal. Med. J

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“…According to 2008 global burden of disease (GBD) estimates, over 600 million have allergic rhinitis, 300 million people have asthma, and 210 million people have COPD (1,6,7). Th e WHO also estimates that COPD is responsible for about 3 million deaths globally in 2011, accounting for about 9.1% of all NCDs deaths (8).…”

Section: Introductionmentioning

confidence: 99%

An Estimate of the Prevalence of COPD in Africa: A Systematic Analysis

Rudan

Basquill

Papana

et al. 2014

COPD: Journal of Chronic Obstructive Pulmonary Disease

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Our findings suggest that COPD is likely to already represent a very large public health problem in Africa. Moreover, rapidly ageing African population should expect a steady increase in the number of COPD cases in the next decade and beyond. The quantity and quality of available evidence does not match the size of the problem. There is a need for more research on COPD prevalence, but also incidence, mortality and risk factors in Africa. We hope this study will raise awareness of COPD in Africa and encourage further research.

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“…Chronic obstructive pulmonary disease (COPD) represents a major public health problem and one of the leading causes of morbidity and mortality worldwide. The population prevalence of COPD is growing in developing countries and especially in North Africa [ 1 – 2 ]. Among the major causes of COPD, the role of tobacco smoking is well recognized and accordingly, recent studies of COPD have been largely focused on the smoking rather than the non-smoking population [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

COPD in Nonsmokers: Reports from the Tunisian Population-Based Burden of Obstructive Lung Disease Study

et al. 2016

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BackgroundIt’s currently well known that smoking and increasing age constitute the most important risk factors for chronic obstructive pulmonary disease (COPD). However, little is known about COPD among nonsmokers. The present study aimed to investigate prevalence, risk factors and the profiles of COPD among nonsmokers based on the Tunisian Burden of Obstructive Lung Disease (BOLD) study.Methods807 adults aged 40 years+ were randomly selected from the general population. We collected information about history of respiratory disease, risk factors for COPD and quality of life. Post-bronchodilator spirometry was performed for assessment of COPD. COPD diagnostic was based on the post-bronchodilator FEV1/FVC ratio, according to the Global Initiative for Obstructive Lung Disease (GOLD) guidelines. The lower limit of normal (LLN) was determined as an alternative threshold for the FEV1/FVC ratio.Results and ConclusionsAmong 485 nonsmokers, 4.7% met the criteria for GOLD grade I and higher COPD. These proportions were similar even when the LLN was used as a threshold. None of the nonsmokers with COPD reported a previous doctor diagnosis of COPD compared to 7.1% of smokers. Nonsmokers accounted for 45.1% of the subjects fulfilling the GOLD spirometric criteria of COPD. Nonsmokers were predominately men and reported more asthma problems than obstructed smokers. Among nonsmokers significantly more symptoms and higher co-morbidity were found among those with COPD. Increasing age, male gender, occupational exposure, lower body mass index and a previous diagnosis of asthma are associated with increased risk for COPD in nonsmokers. This study confirms previous evidence that nonsmokers comprise a substantial proportion of individuals with COPD. Nonsmokers with COPD have a specific profile and should, thus, receive far greater attention to prevent and treat chronic airway obstruction.

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Burden of Chronic Respiratory Diseases (CRD) in Middle East and North Africa (MENA)

Cited by 11 publications

References 9 publications

The epidemiology of noncommunicable respiratory disease in sub-Saharan Africa, the Middle East, and North Africa

The epidemiology of noncommunicable respiratory disease in sub-Saharan Africa, the Middle East, and North Africa

An Estimate of the Prevalence of COPD in Africa: A Systematic Analysis

COPD in Nonsmokers: Reports from the Tunisian Population-Based Burden of Obstructive Lung Disease Study

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