Burden of Rheumatic Diseases in A Rural Community of Bangladesh

Ahmed, M. S.; Haq, Syed Atiqul; Islam, Md. Nazrul; Banik, Sree Krisna

doi:10.3329/jom.v15i2.20685

Cited by 4 publications

(5 citation statements)

References 9 publications

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“…On the other hand, many researches shows the female predominance in patients with MS in Bangladesh. 13,14 In the present research, majority (more than 80%) patients of CRHD with MS had under BMI as most of the patients in previous researches were under weight. The findings of the present research reflects the present health awareness of study population attending to the doctor as well as came to tertiary level hospital like as BSMMU.…”

Section: Bmi Of Study Subjectssupporting

confidence: 46%

Comparison of the Appendicular Emptying Velocity of Left Atrium in patient with moderate versus severe chronic rheumatic mitral stenosis measured by pulsed wave Doppler in Transesophageal echocardiography

et al. 2022

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Background: Left atrial appendage (LAA) is considered the “most lethal human appendage” as it causes significant mortality and morbidity in chronic rheumatic mitral stenosis patients due to cardiogenic cerebral infract. Presence of LAA dysfunction has been shown to be a strong predictor of thrombus formation and the risk of embolic event, even if no clot is found at the time of initial examination. LAA emptying velocity are measured by trans esophageal echocardiography (TEE) represent as a surrogate marker for left atrial(LA) function .LAA emptying velocities (contraction velocity) < 20cm/s are associated with risk of spontaneous echo contrast(SEC), LAA thrombus, and subsequent cardio embolic events. So early detection of low emptying velocity without SEC or LA thrombus can reduce mortality & morbidity related to cardio embolic stroke and also helps in further management procedure like cardio version etc. So we will compare LAA emptying velocity moderate versus severechronic rheumatic mitral stenosis patients in our population for further attention. Objective: To assess emptying velocity of LAA in patient with moderate versus severe chronic rheumatic mitral stenosis, from a Bangladesh health service perspective. Method: This was a cross sectional study which was conducted in UCC, BSMMU during the period of from February 2019 to September 2019 in Echo lab . Study Procedure: We were enrolled 33 CRHD with MS (moderate to severe) patients who underwent TEE and met inclusion & exclusion criteria. The purpose of the study was explained to each subject & informed written consent was obtained. After getting consent relevant history, physical examination and preprocedural investigation was obtained in predesigned structured data collection sheet. TEE was done with Vivid E9® machine. Pulse wave Doppler was position at the tip of the LAA and then emptying velocity of LAA moderate and severe were compared. Outcome measure: Among 33 patients, 3 patients were excluded due to outlier and inadequate data.. In chronic rheumatic mitral stenosis in moderate versus severe cases average LAA emptying velocities were significantly higher moderate CRHD with MS compare to severe CRHD with MS,(26.57±4.91;31.12±5.04), P=0.018. Conclusion:Appendicular emptying velocity of LAA significantly lower in severe CRHD with MS compare to moderate CRHD with MS and it has temporal relation with MS severity. It can be used as a reliable, simple and sami-invasive tool to early predict severity and prevent complication in CRHD with MS as well as for prophylactic measured taken. University Heart Journal 2022; 18(2): 73-79

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Section: Bmi Of Study Subjectssupporting

confidence: 46%

Comparison of the Appendicular Emptying Velocity of Left Atrium in patient with moderate versus severe chronic rheumatic mitral stenosis measured by pulsed wave Doppler in Transesophageal echocardiography

et al. 2022

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“…The search generated 1,160 articles after removal of duplicates, and 138 articles were selected for full‐text review (Figure 1). From these, 54 articles were included for data synthesis (12–65) and are described in Supplementary Table 2, available on the Arthritis Care & Research website at https://doi.org/10.1002/acr.24513, with some studies reporting ≥1 outcome of interest. In total, 35 studies described an epidemiology outcome (n = 32 prevalence and n = 4 incidence), 15 described RA clinical characteristics of rural or remote populations, and 15 studies reported on health service utilization.…”

Section: Resultsmentioning

confidence: 99%

“…The search generated 1,160 articles after removal of duplicates, and 138 articles were selected for full‐text review (Figure 1 ). From these, 54 articles were included for data synthesis ( 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 ) and are described in Supplementary Table…”

Section: Resultsmentioning

confidence: 99%

“…In a German population, incidence was reported as a proportion, with 0% of male patients and 6% of female patients developing RA over a 5‐year observation period ( 21 ). In 2 rural Bangladesh populations, the rate was 0.48 per 100 person‐years (95% confidence interval [95% CI] 0.27–0.85) ( 30 ) and 0.12 per 100 person‐years (95% CI 0.1–0.7) ( 65 ). In a Taiwanese population, the incidence rate was estimated at 0.02 per 100 person‐years (95% CI 0.02–0.3), which was not significantly different from that of the comparator urban population (relative risk 1.04 [95% CI 0.87–1.24], P = 0.67) ( 35 ).…”

Section: Resultsmentioning

confidence: 99%

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Global Rural and Remote Patients With Rheumatoid Arthritis: A Systematic Review

Pianarosa

Chomistek

Hsiao

et al. 2022

Arthritis Care & Research

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Objective Rural and remote patients with rheumatoid arthritis (RA) are at risk for inequities in health outcomes based on differences in physical environments and health care access potential compared to urban populations. The aim of this systematic review was to synthesize epidemiology, clinical outcomes, and health service use reported for global populations with RA residing in rural and remote locations. Methods Medline, Embase, HealthStar, the Cumulative Index to Nursing and Allied Health Literature (CINAHL), and the Cochrane Library were searched from inception to June 2019 using librarian‐developed search terms for RA and rural and remote populations. Peer‐reviewed published manuscripts were included if they reported on epidemiologic, clinical, or health service use outcomes. Results Fifty‐four articles were included for data synthesis, representing studies from all continents. In 11 studies in which there was an appropriate urban population comparator, rural and remote populations were not at increased risk for RA; 1 study reported increased prevalence, and 5 studies reported decreased prevalence in rural and remote populations. Clinical characteristics of rural and remote populations in studies with an appropriate urban comparator showed no significant differences in disease activity measures or disability, but 1 study reported worse physical function and health‐related quality of life in rural and remote populations. Studies reporting on health service use provided evidence that rural and remote residence adversely impacts diagnostic time, ongoing follow‐up, access to RA‐care–related practitioners and services, and variation in medication access and use, with prominent heterogeneity noted between countries. Conclusion RA epidemiology and clinical outcomes are not necessarily different between rural/remote and urban populations within countries. Rural and remote patients face greater barriers to care, which increases the risk for inequities in outcomes.

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“…In UK, prevalence is around 13 percent [3]. According to a survey by Ahmed M, et al rheumatic diseases are more common in the rural areas of Bangladesh than in the big cities, affecting at least 1.6 percent of the total population [4]. Another study by Ahmed S, et al.…”

Section: Introductionmentioning

confidence: 99%

Role of Osteoclast Regulation in Arthritis – A Review

Iqbal¹

2021

Mathews Journal of Pharmaceutical Science

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Osteoclasts are multinucleated bone degrading cells that differentiate from monocyte/macrocphage precursors of the hematopoietic system. From the bone marrow, precursors of osteoclasts move towards the systemic circulation through the attraction towards chemokines in the blood and are later taken up by various resorption sites where they undergo differentiation into osteoclasts. Macrophage colony stimulating factor (M-CSF) and receptor activator of nuclear factor-ҡB ligand (RANKL) play a pivotal role in the differentiation and activation of osteoclasts. M-CSF induces the expression of RANK on myeloid progenitors and RANKL activates its receptor to initiate osteoclast differentiation. RANKL also stimulates bone resorption in mature osteoclasts. Rheumatoid arthritis is an autoimmune disease that leads to severe bone destruction mediated by the abnormal activation of osteoclasts. Synovial tissues in rheumatoid arthritis produce inflammatory cytokines that act on osteoclast precursor cells, thereby differentiating them into osteoclasts by cooperating with RANKL. Bone resorption proceeds uncontrollably through the abnormal activity of osteoclasts, leading to bone and cartilage destruction in the joints. The involvement of osteoclasts in the pathogenesis of rheumatoid arthritis has been further confirmed through animal model studies.

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Burden of Rheumatic Diseases in A Rural Community of Bangladesh

Cited by 4 publications

References 9 publications

Comparison of the Appendicular Emptying Velocity of Left Atrium in patient with moderate versus severe chronic rheumatic mitral stenosis measured by pulsed wave Doppler in Transesophageal echocardiography

Comparison of the Appendicular Emptying Velocity of Left Atrium in patient with moderate versus severe chronic rheumatic mitral stenosis measured by pulsed wave Doppler in Transesophageal echocardiography

Global Rural and Remote Patients With Rheumatoid Arthritis: A Systematic Review

Role of Osteoclast Regulation in Arthritis – A Review

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