2014
DOI: 10.1161/circep.113.001421
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Burden of Sudden Cardiac Death in Persons Aged 1 to 49 Years

Abstract: Background-Knowledge of the burden and causes of sudden cardiac death (SCD) is sparse in persons aged <50 years; better understanding is needed to lower the risk of SCD. The aim of this study was to report SCD incidence rates and autopsy findings in persons aged 1 to 49 years. Methods and Results-All deaths in persons aged 1 to 49 years were included in 2007 to 2009. Death certificates were reviewed by 2 physicians. History of previous admissions to hospital was assessed, and discharge summaries were read. Sud… Show more

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Cited by 165 publications
(125 citation statements)
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“…25,26 In addition to our study, the Veneto study is a prospective effort, and the Danish study is retrospective in nature. In the Danish study, the proportion of SCD in structurally normal hearts is significantly larger than in our study and the Veneto study.…”
Section: Discussionmentioning
confidence: 99%
“…25,26 In addition to our study, the Veneto study is a prospective effort, and the Danish study is retrospective in nature. In the Danish study, the proportion of SCD in structurally normal hearts is significantly larger than in our study and the Veneto study.…”
Section: Discussionmentioning
confidence: 99%
“…4,5 There is a similar incidence in Europe, with reports of out-of-hospital cardiac arrest ranging from 0.04 % to 0.1 %. [6][7][8] When the aetiological definition is limited to coronary artery disease (CAD) and its tachyarrhythmic burden, the estimate is <200,000 events per year. 9 Approximately 50 % of all cardiac deaths are sudden, and this proportion has remained unchanged despite the overall decrease in cardiovascular mortality in recent decades.…”
Section: Epidemiologymentioning
confidence: 99%
“…12 In Denmark, the annual incidence of SCD is 2.3 for people aged 1-35 years and 21.7 for people aged 36-49 years. 6 Population movement, and especially major train stations, are associated with a higher risk of SCD. 13 The main problem with SCD is that the majority of out-of-hospital sudden cardiac arrests occur among patients in whom cardiac arrest is the first clinical expression of the underlying disease or those in whom disease has previously been identified but classified as low risk.…”
Section: Department Of Defense Cardiovascular Death Registry In the Umentioning
confidence: 99%
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“…Retrospective analysis of death certification, autopsy reports, and registry data estimated that 31% of autopsied SCD cases in Danes aged 1-49 years were unexplained and attributed to SADS. 10 Conversely, in 79% of 197 cases of young SCD in Italy, histologic analysis yielded a structural diagnosis such as cardiomyopathy or focal myocarditis; 6% were unexplained and attributable to SADS. 11 In the Veneto region of Italy, studies have implicated arrhythmogenic right ventricular cardiomyopathy (ARVC) in 20% of sudden deaths among athletes and the young.…”
Section: Introductionmentioning
confidence: 99%