Burkitt’s Lymphoma Presenting as a Maxillary Swelling in a HIV-Negative Adult

Non-Hodgkin's lymphoma (NHL) is a malignant neoplasm of the lymphoid tissue and is one of the most prevalent cancers seen worldwide. 1 A rare and aggressive variant of this neoplasm, Burkitt lymphoma (BL), develops from germinal or post-germinal B cells and is characterized by MYC oncogene translocation. 2 BL is further classified into 3 epidemiologically dissimilar types with different population targets: endemic-, sporadic-, and immunodeficiency-associated BL. 3 The sporadic subtype which yearly has an incidence of around 3 cases out of a million people, typically occurs in children and comprises less than 1% of all adult NHLs. 4 Only 8.9% of the head and neck neoplasms are lymphomas, 1.9% of them occurring in oral cavity. 5 Oral lymphomas usually occur in the tonsils, palate, gingiva, or jaws and may be seen centrally in bone or peripherally in soft tissue. Most of them are "diffuse large B-cell lymphomas" (DLBCL) or plasmablastic lymphomas, the latter being frequent in immunodeficient patients. 6,7 Endemic BL also involves the head and neck site especially the jaws frequently. However, sporadic BL rarely has a presentation in this region. 8 In this case report, we present an adult patient with sporadic BL involving the mandible. | CASE REPORTA 49-year-old white man was referred to the maxillofacial surgery department of Tehran University in July 2019 with a chief complaint of vague pain in the left mandibular area and

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Mandibular sporadic Burkitt lymphoma in an adult patient: A case report and review of the literature

Azimi

Razmara

Derakhshan

et al. 2021

Clinical Case Reports

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Burkitt’s Lymphoma Presenting as a Maxillary Swelling in a HIV-Negative Adult

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References 34 publications

Mandibular sporadic Burkitt lymphoma in an adult patient: A case report and review of the literature

Mandibular sporadic Burkitt lymphoma in an adult patient: A case report and review of the literature

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