Burn wound infections and Pseudomonas aeruginosa

Salerian, Alen J

doi:10.1016/j.burns.2019.07.008

Cited by 14 publications

(11 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This observation is supported by recent studies suggesting that decomposer species including Pseudomonas are not foreign Invaders from the environment and they represent evolution of common microorganisms during mammalian decomposition [7][8][9]. For instance, it has been shown that, mammalian decomposition takes place in sterile soil or in tightly insulated pig carcasses wrapped in plastic, submerged in water, suggesting that some of decomposer species are endogenous and evolve from resident flora [7][8][9].…”

Section: Evolution Simple Microbes To Complex Microbesmentioning

confidence: 61%

“…Charles Darwin suggested that all species are related and some species including microorganisms may evolve from less complex microorganisms [4]. Thus, it seems quite likely that some microbes -such as pseudomonas aeruginosa which has a larger genome and greater cellular and functional complexity than common bacteria [5,6] may evolve from human flora as observed in mammalian decomposition [7][8][9]. This observation is supported by recent studies suggesting that decomposer species including Pseudomonas are not foreign Invaders from the environment and they represent evolution of common microorganisms during mammalian decomposition [7][8][9].…”

Section: Evolution Simple Microbes To Complex Microbesmentioning

confidence: 99%

“…Thus, it seems quite likely that some microbes -such as pseudomonas aeruginosa which has a larger genome and greater cellular and functional complexity than common bacteria [5,6] may evolve from human flora as observed in mammalian decomposition [7][8][9]. This observation is supported by recent studies suggesting that decomposer species including Pseudomonas are not foreign Invaders from the environment and they represent evolution of common microorganisms during mammalian decomposition [7][8][9]. For instance, it has been shown that, mammalian decomposition takes place in sterile soil or in tightly insulated pig carcasses wrapped in plastic, submerged in water, suggesting that some of decomposer species are endogenous and evolve from resident flora [7][8][9].…”

Section: Evolution Simple Microbes To Complex Microbesmentioning

confidence: 99%

See 2 more Smart Citations

Infections Independent of Contamination: From Organic Matter, Evolution or Stem Cells

Salerian¹

2021

Appl Cell Biol

View full text Add to dashboard Cite

This study presents evidence to propose that some human infections may derive Independent of contamination by invading pathogens. Diverse data suggest multiple pathways Independent of contamination may generate human infections. For instance, the first microorganisms that emerged from lifeless organic matter 3.6 billion years ago indicated transformation of lifeless organic matter to micro organisms. Viral infections do correspondent to a lifeless protein particle in a cell of a complex multi- cellular organism reproducing and spreading infections to other complex multi- cellular organisms. Some microbes -such as pseudomonas aeruginosa with a larger genome and greater functional complexity than common bacteria -may evolve from human flora as observed in mammalian decomposition in sterile soil. For, decomposer species are not foreign Invaders from the environment and they represent evolution of common microorganisms during mammalian decomposition. Human cells may produce microorganisms consistent with a proven genetic link between humans cells and the Christensenellaceae (a family in the phylum Firmicutes). Human stem cells which are capable to differentiate to epithelial cells and cancer and have the essentials to produce microbes are the most likely candidates to produce microorganisms. What may be almost certain and not experimentally validated is the possibility that infections have multiple pathways of origin independent of contamination. Most nosocomial and opportunistic infections may be endogenous. Our knowledge may demolish the dogma of contamination by foreign microbes as the exclusive source of infections and pave novel avenues to prevent and treat diverse infections.

show abstract

Section: Evolution Simple Microbes To Complex Microbesmentioning

confidence: 61%

Section: Evolution Simple Microbes To Complex Microbesmentioning

confidence: 99%

Section: Evolution Simple Microbes To Complex Microbesmentioning

confidence: 99%

See 1 more Smart Citation

Infections Independent of Contamination: From Organic Matter, Evolution or Stem Cells

Salerian¹

2021

Appl Cell Biol

View full text Add to dashboard Cite

show abstract

“…In spite of the fact that S. aureus remains a common cause of early burn wound contamination, Pseudomonas aeruginosa and Proteusmirabilis from the patient's endogenous gastrointestinal vegetation and/or a natural source is the foremost common cause of burn wound contaminations in numerous centers.The rate of diseases due to less commonly experienced organisms, counting other gram-positive and gram-negative microscopic organisms, fungi, and viruses, has too expanded relentlessly in subsequent decades [9].…”

Section: Introductionmentioning

confidence: 99%

Isolation and Identification of Bacterial Burn Wound Infection in Iraqi Patient

Jenan A. Ghafil,

May. T. flieh

2021

Indian Journal of Forensic Medicine & Toxicology

View full text Add to dashboard Cite

Burns are one of the most common and devastating forms of trauma. Patients with serious thermal injury require immediate specialized care in order to minimize morbidity and mortality.In current study, 120 samples were collected from 120 patients suffering from contaminated burns. The study was conducted after obtaining ethical approvals from the ethics committee in the Department of Biology, College of Science, University of Baghdad as well after obtaining the patients 'consent. Samples are collected from patients after they have stopped using antibiotics for 48 hours.After the swabs had been cultured on different media, conventional biochemical tests to identify bacterial isolates and antimicrobial sensitivity to the most common antibiotics were performed by vitek 2 compact .The results showed that the highest percentage of bacterial species was Proteus mirabilis (31.1 %). The percentage of isolation of P. aeruginosa was 17.78%. The lowest percentage of bacterial isolates that isolated from infected wound was found in case of Staphylococcus aureus, Pseudomonas fluorescens, Acinetobacterhaemolyticus, Burkholderiacepacia, Salmonella ser. gallinarum, Sphingomonaspaucimobilis, Comamonas testosterone with 2.2 % for each isolate.

show abstract

“…Burn infection is one of the most common and destructive forms of acute trauma. Because of bacterial infection, it prevents the wound from healing and may even lead to death, so throughout the history of human health, burn infection has always been a constant threat [2] [3]. Although artificial skin can replace the role of skin, solve the *Corresponding author.…”

Section: Introductionmentioning

confidence: 99%

An Antibacterial Wound Dressing Based on GS-SF Composite Scaffold

Jiang¹,

Chen²,

Bin³

2020

Health

View full text Add to dashboard Cite

Although the treatment of burn wounds has made great progress, the incidence of wound infection is still the main cause of high mortality. In this study, a silk fibroin (SF) scaffold wound dressing incorporated with Gentamicin Sulfate (GS) was developed for the treatment of burn infected wounds, in which GS was used as anti-bacterial agent. GS was mixed with silk fibroin solution and then processed into GS-SF composite scaffold via electro-spinning. The results showed the scaffold exhibited uniform polyporous morphology with 80% porosity. Induced by methanol, the scaffold presented much improved mechanical properties and stability to protease XIV. More important, the scaffold presented significant growth inhibition on both Gram-positive (Staphylococcus aureus) and Gram-negative (Pseudomonas aeruginosa and Escherichia coli) bacteria.

show abstract

Burn wound infections and Pseudomonas aeruginosa

Cited by 14 publications

References 14 publications

Infections Independent of Contamination: From Organic Matter, Evolution or Stem Cells

Infections Independent of Contamination: From Organic Matter, Evolution or Stem Cells

Isolation and Identification of Bacterial Burn Wound Infection in Iraqi Patient

An Antibacterial Wound Dressing Based on GS-SF Composite Scaffold

Contact Info

Product

Resources

About