Burning Mouth Syndrome

Mock, David; Chugh, Deepika

doi:10.4248/ijos10008

Cited by 47 publications

(37 citation statements)

References 19 publications

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“…Burning mouth syndrome is associated with nutritional deficiencies, including vitamin B 1 , B 2 , B 6 and B 12 deficiencies. However, recent studies have shown that zinc deficiency can also lead to BMS.…”

Section: Introductionmentioning

confidence: 99%

“…Metabolic endocrine and nutritional disorders might give rise to BMS. Some nutritional disorders include deficiencies in iron, zinc and vitamin B group, especially vitamin B 12 (6,7). pears in some patients with BMS with deficiencies mentioned previously, eliminations of systemic, local and psychological factors has results in alleviation of or decrease in BMS symptoms (8).…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of the Effect of Oral Zinc Sulfate on Burning Mouth Syndrome: A Double Blind Randomized Clinical Trial

FatemeArbabi-Kalati¹,

BahramTahmtan²

2015

DCEJ

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Background: Burning Mouth Syndrome (BMS) is a common condition that affects menopausal women and patients experience a severe burning sensation in their mouth. So far there have been no definitive treatment for this disease. Objectives: The present study was undertaken to evaluate the efficacy of zinc supplement in improving the symptoms of burning mouth syndrome. Patients and Methods: Sixty patients were enrolled in this study; they were randomly divided to two groups. Patients in the intervention group received replacement therapy twice daily, which continued for three months. In the control group, placebo capsules, which were completely similar to zinc sulfate capsules, were administered two times daily. Results: Burning sensation severity in the two groups after the intervention was significantly different (P = 0.001). Conclusions: It can be concluded that zinc supplement might decrease the intensity of burning mouth syndrome in patients with zinc deficiency.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Evaluation of the Effect of Oral Zinc Sulfate on Burning Mouth Syndrome: A Double Blind Randomized Clinical Trial

FatemeArbabi-Kalati¹,

BahramTahmtan²

2015

DCEJ

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“…A wide variety of pathogenic conditions therefore must be included such as local irritation; various mucocutaneous diseases; nutritional, metabolic, or endocrine disorders; xerostomia; and dysgeusia [3]. Kampo medicine, Japanese traditional herbal medicine, which originated in China, treats BMS based on Kampo-specific diagnostics, regardless of the pathogenesis determined on the basis of conventional medicine.…”

Section: Introductionmentioning

confidence: 99%

A Valid Approach in Refractory Glossodynia: A Single-Institution 5-Year Experience Treating with Japanese Traditional Herbal (Kampo) Medicine

Okamoto

Chino

Hirasaki

et al. 2013

Evidence-Based Complementary and Alternative Medicine

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Glossodynia is often refractory to conventional medicine, and there is only limited evidence to guide clinicians in its management. Patients with refractory glossodynia are often introduced to Japanese traditional herbal (Kampo) medicine experts under such circumstances because Kampo medicine has become known in Japan to be effective in treating a wide variety of symptoms refractory to conventional medicine. Herein, we report our single-institution 5-year experience treating patients with Kampo medicine for primary glossodynia that was refractory to conventional medicine. We found that 69.2% of patients reported a beneficial effect of Kampo medicine on glossodynia, and the average onset of improvement was 8.0 ± 7.7 weeks after starting Kampo treatment. The top two frequently used Kampo medicines for glossodynia were seinetsuhokito and mibakuekkito among high responders who showed a decrease of severity by 50% or more. The top four most overlapped herbs among effective Kampo medicines for glossodynia were Glycyrrhiza Root, Ginseng Root, Hoelen, and Atractylodes (lancea) Rhizome, which compose an essential Kampo prescription called shikunshito. Although more research is required to further clarify the effectiveness of Kampo medicine, it has valid efficacy even in cases of glossodynia that remain incurable by conventional treatments.

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“…4 It is most often bilateral, and does not conform to a single peripheral nerve distribution. 3 Burning mouth syndrome is associated in two thirds of cases with xerostomia and dysgeusia despite normal quantity of salivation, 5 and exhibits impaired olfactory perception.…”

mentioning

confidence: 99%

“…3 It affects more women, with a sex ratio of 7:1, 3,6 especially during perimenopause or postmenopause. 4 The age of onset is earlier in men than women (about 30 vs 50 years). 3 Burning mouth syndrome presents a difficult diagnosis for many clinicians for several reasons.…”

mentioning

confidence: 99%

Burning Mouth Syndrome

Ducasse

Courtet

Olié

2013

Regional Anesthesia and Pain Medicine

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Primary burning mouth syndrome (BMS) is defined as an "intraoral burning for which no medical or dental cause was found." Lifetime prevalence ranges from 3.7% to 18% - 40% in the elderly. There is no consensus among experts on the diagnostic criteria of BMS, the etiology is poorly understood, and there are no existing clinical guidelines. Therefore, BMS is often underdiagnosed and its management complex. For patients with BMS, this lack of clinical expertise may result in decreased quality of life and increased psychological distress.We conducted a systematic review to identify clinical features, pathophysiology, and therapeutic strategies for BMS. We discuss the multifactorial origin, involving peripheral nerve dysfunction and hormonal dysfunction, as well as psychological traits. We also describe the results of randomized clinical trials for each treatment through a pathophysiologic approach. This review should help clinicians recognize BMS, understand its pathophysiology, and gain an enhanced scientific understanding of therapeutic alternatives.

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Burning Mouth Syndrome

Cited by 47 publications

References 19 publications

Evaluation of the Effect of Oral Zinc Sulfate on Burning Mouth Syndrome: A Double Blind Randomized Clinical Trial

Evaluation of the Effect of Oral Zinc Sulfate on Burning Mouth Syndrome: A Double Blind Randomized Clinical Trial

A Valid Approach in Refractory Glossodynia: A Single-Institution 5-Year Experience Treating with Japanese Traditional Herbal (Kampo) Medicine

Burning Mouth Syndrome

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