C-Reactive Protein as a Biochemical Criterion of a General Inflammatory Syndrome in Lyme Disease in Children

Abstract

The aim of the study – to improve the methods of non-specific biochemical markers of Lyme disease.
 Materials and Methods. A group of children (62) aged from 1 to 14 years was observed for the identification of pathogens of blood-borne infections among children. C-reactive protein (CRP) is a protein and acute phase reagent as well as the information base for the interpretation and analysis of clinical observations of CRP.
 Results and Discussion. There were studied the concentrations of acute-phase response proteins including CRP in children with Lyme disease. We found that circulating of CRP levels as well as concentrations> 3 mg/ml was significantly higher in the group of children with Lyme arthritis cohort than in the control group (P <0.05).
 Conclusions. C-reactive protein concentration is a very useful but non-specific biochemical marker of inflammation, the measurement of which makes an important contribution to the screening of Lyme borreliosis in children.