Abstract. We give new characterizations to ensure that a free product of groups with amalgamation has a simple reduced group C * -algebra, and provide a concrete example of an amalgam with trivial kernel, such that its reduced group C * -algebra has a unique tracial state, but is not simple.Moreover, we show that there is a radical class of groups for which the reduced group C * -algebra of any group is simple precisely when the group has a trivial radical corresponding to this class.