Cadmium(II) complexes containing N′-substituted N,N-di(2-picolyl)amine: The formation of monomeric versus dimeric complexes is affected by the N′-substitution group on the amine moiety

A Fluorescent Sensor Array for the Discrimination of Nucleotide Phosphates

“…In previous work, we have shown that peptide 1 • Zn 2 (Scheme 1), which contains a covalently linked coumarin catechol, is capable of sensing phosphate derivatives through a fluorogenic intramolecular indicator displacement mechanism [28] and that linear peptide receptors displaying the bis[Zn(II)DPA)] binding motif bind to a range of nucleotide phosphates with varying binding affinities. [29][30][31][32][33][34] The dipicolylamino groups present in 1 are also known to bind a range of other metal ions, including cadmium(II), nickel(II) and cobalt(II) [35][36][37] and some of these alternative metal complexes have been shown to bind to phosphate derivatives. [3] We reasoned that complexes of peptide 1 with a panel of metal ions would have different affinities for phosphate species and/ or result in differences in the fluorescent response obtained upon addition of phosphates, resulting in a set of readily accessible cross-reactive array elements.…”

Colorimetric and fluorescent probes for real-time naked eye sensing of copper ion in solution and on paper substrate

“…All reagents and solvents were commercially purchased, and the solvents were used after appropriate distillation or purification. The intermediates BPA, 4-(bis(pyridin-2-ylmethyl)amino)benzaldehyde (BPA-CHO) and TCF were synthesized according to the literature [ 26 – 28 ]. Stock solutions of compound BT (1 mM) were prepared in dimethylsulfoxide, then diluted to 10 µM in ethanol/HEPES (1 : 4 v/v) buffer (pH 7.2).…”

Evaluation of oxygen-containing pentadentate ligands with pyridine/quinoline/isoquinoline binding sites via the structural and electrochemical properties of mononuclear copper(ii) complexes

“…In contrast to the numerous examples of all-nitrogen compounds, oxygen-containing tetra- and pentadentate ligands have been scarcely investigated. 46–52 Although the high electronegativity of oxygen in comparison with nitrogen significantly reduces the electron-donating ability of ether oxygen binding sites, careful ligand design of oxygen-containing ligands could be a potential strategy for providing an extended ligand library with unique properties. The weak donating ability of the oxygen atom affords hemi-labile sites to the metal centre, altering the electronic and structural properties of the whole ligand.…”