Calcio-herbal formulation, Divya-Swasari-Ras, alleviates chronic inflammation and suppresses airway remodelling in mouse model of allergic asthma by modulating pro-inflammatory cytokine response

Immunity against COVID-19: Potential role of Ayush Kwath

“…It has been also found to increase bioavailability, thus enhance the therapeutic efficacy of many drugs, vaccines and nutrients and have immune-modulatory, anti-oxidant, antiplatelets, antihypertensive, anti-asthmatic, antipyretic, analgesic, anti-carcinogenic, anti-inflammatory, anti-diarrheal, antispasmodic, anxiolytic, antidepressants, hepatoprotective, anti-ulcer, anti-thyroids, anti-apoptotic, anti-metastatic, antimutagenic, antibacterial, antifungal and anti-amoebic properties [ [62] , [63] , [64] , [65] ]. The extract and its constituents like piperine, regulate the balance of the cytokines production of Th1, Th2, Th17, and Treg cells, reduce the accumulation of inflammatory cells, inhibit the expressions of GATA3, IL-4, IL-6, IL-1β, RORγt, IL-17A and TNF-α, increase INF-γ and IL-10 secretions in BALF (Broncho-alveolar lavage fluid) and increase macrophage activation and T and B cell proliferation [ 63 , 66 ].…”

Biological Properties of a Citral-Enriched Fraction of Citrus limon Essential Oil

“…GSH/GSSG is considered a key indicator of oxidative stress [56,57]. In particular, the increase in the ratio indicates a decrease in cellular oxidative stress [58][59][60]. As shown in Figure 5, we found that in LPS-treated THP1 M0 cells the pre-treatment for 2 h with Cfr-LEO induced the increase of the GSH/GSSG ratio compared to no pre-treated cells, indicating the ability of Cfr-LEO to counteract the LPS-induced oxidative stress.…”

Calcio-Herbal Medicine Divya-Swasari-Vati Ameliorates SARS-CoV-2 Spike Protein-Induced Pathological Features and Inflammation in Humanized Zebrafish Model by Moderating IL-6 and TNF-α Cytokines

“…Essential oils from P. integerrima have been known to exert an anti-asthmatic activity due to their action on reducing TNF-α activity. 49,50 TNF-α has been implicated in several aspects of airway pathology including asthma 51 and retrospective analysis of plasma levels in cases of SARS-CoV-2, has shown increasingly higher levels of TNF-α with increasing severity of the infection. 52 Whole Cressa cretica plant is also known to Table 7 Table 7 Phytocompounds Present in Divya-Swasari-Vati Medicinal Formulation as Determined by HPLC ( Figure 11 have broncho-dilatory activity, while the aerial parts contain many active compounds including coumarin derivatives and have anti-inflammatory and anti-oxidant activities.…”

“…Kapadrak Bhasma, Abhrak Bhasma, Godanti Bhasma, and Mukta-Shukti Bhasma, are calcium rich and are highly anti-inflammatory in nature. 49 Sphatika Bhasma is derived from calcined form of Alum and is known for its hemostatic and anti-inflammatory properties along with Tankan Bhasma (herbally processed ash from calcined borax), have been shown to have therapeutic efficacy in "disease of throat" and "disease of palate". 62 Praval pishti which is processed coral calcium, is used for the treatment of inflammation, cough due to phthisis, and several other ailments.…”