Calcitonin in the Treatment of Transient Osteoporosis of the Hip

Arayssi, Thurayya; Tawbi, Hussein A.; Usta, Ihab M.; Hourani, Mukbil

doi:10.1053/sarh.2002.50014

Cited by 71 publications

(48 citation statements)

References 76 publications

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“…In our patient, laboratory tests were within normal limits and there were not any systemic finding. On MRI, the extension of the signal intensity changes from the metaphysis to the epiphysis also favors TOH as in our case, and differentiates the disease from malignancies and septic arthritis which are usually located in the metaphysis (2,6,14).…”

Section: Discussionsupporting

confidence: 59%

“…MRI shows abnormal findings before conventional radiography, as early as 48 hours after the onset of TOH (14). Edema and fat necrosis in the femoral region result in a reduced T1 signal, whereas T2 signals are increased due to osteopenia extending from the femoral head to the intertrochanteric region which is diffuse and homogeneous as in our case.…”

Section: Discussionmentioning

confidence: 43%

“…In AVN, there is no homogeneity, and the involvement is segmental or focal in the anterosuperior (subchondral) region of the femoral head. Additionally, the subchondral collapse (sign of half-moon), pathognomonic for avascular necrosis which particularly develops in the advanced phases, is not seen in TOH (3,6,14). Since our patient was in the early stage of the disease, plain radiography of the pelvis revealed normal findings.…”

Section: Discussionmentioning

confidence: 70%

“…Additionally, inflammatory joint diseases, fractures of the femoral neck, reflex sympathetic dystrophy, pigmented villonodular synovitis and synovial chondromatosis should also be taken into consideration (9,13,14). History, physical examination, radiological analysis, laboratory tests and clinic course of the condition are also important in diagnosis.…”

Section: Discussionmentioning

confidence: 99%

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Gebe Olmayan Bir Kadında Kalçanın İdiopatik GeçiciOsteoporozu: VakaÇalışması

Erdem¹,

Özdemirel²,

Nacır³

et al. 2013

Tftr

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Sum maryTransient osteoporosis of the hip (TOH) is a rare disease affecting women in the third trimester of pregnancy as well as middle-aged men. TOH is associated with hip pain and temporary osteopenia apparent on radiology without joint space narrowing or destruction of the hip. Pregnancy is the only recognized risk factor for women. It typically runs a benign course with eventual resolution of symptoms. Radiographs may be unrevealing early in its course. Therefore, transient osteoporosis may be confused with many other conditions such as avascular necrosis. In early stages, it is important to distinguish between these two conditions to order to decide on an appropriate treatment plan. In this report, we present a 35-year-old woman who had TOH, without any risk factor including pregnancy, and showed sufficient improvement with conservative treatment. Turk J Phys Med Rehab 2013;59:157-60. Key Words: Transient osteoporosis, hip, pregnancy ÖzetKalçanın geçici osteoporozu (KGO) öncelikle orta yaşlı erkekleri ve gebeliğin üçüncü trimestrindeki dönemindeki kadınları etkileyen nadir bir hastalıktır. KGO kalça ağrısı ve radyolojik olarak eklem aralığında daralma veya destrüksiyon olmaksızın ortaya çıkan geçici osteopeni ile ilişkilidir. Kadınlar için tanımlanmış tek risk faktörü gebeliktir. Tipik olarak semptomların kendiliğinden rezolüsyonu ile benign bir seyir gösterir. Radyografiler erken dönemde belirti vermeyebilir. Bu nedenle, geçici osteoporoz avasküler nekroz gibi çok sayıda diğer hastalıklarla karışabilir. Erken dö-nemlerde bu iki hastalığın birbirinden ayırt edilmesi uygun tedavi planı-nın seçilebilmesi için önemlidir. Bu yazıda, gebelik de dahil olmak üzere herhangi bir risk faktörü olmayan ve konserevatif tedavi ile yeterli iyileşme gösteren KGO'lu 35 yaşındaki kadın hasta sunulmuştur.Türk Fiz T›p Re hab Derg 2013;59:157-60 Re hab 2013;59:157-60 Türk Fiz T›p Re hab Derg 2013;59:157-60 Turk J Phys Med

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Section: Discussionsupporting

confidence: 59%

Section: Discussionmentioning

confidence: 43%

Section: Discussionmentioning

confidence: 70%

Section: Discussionmentioning

confidence: 99%

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Gebe Olmayan Bir Kadında Kalçanın İdiopatik GeçiciOsteoporozu: VakaÇalışması

Erdem¹,

Özdemirel²,

Nacır³

et al. 2013

Tftr

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“…Before the advent of MRI, radionuclide bone scans were used for the diagnose of TOH due to their higher sensitivity in comparison to X-rays. Radionuclide bone scans are also able to differentiate between TOH and avascular necrosis as the uptake is more pronounced in TOH and there is no evidence of "cold spots" which are usually seen in avascular necrosis [11].…”

Section: P Sachsanidis Et Al Open Journal Of Obstetrics and Gynecologymentioning

confidence: 99%

Recurrent Transient Osteoporosis during Pregnancy and Treatment with Oral Bisphosphonates: A Case Report

Sachsanidis¹,

Tartagni²,

Graf³

2017

OJOG

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Transient osteoporosis of the hip (TOH), also known as "Bone marrow edema Syndrome", is a rare disorder mainly affecting pregnant women in their third trimester, as well as middle-aged, overweight men. A 30-year-old Caucasian female G2P2, with history of transient osteoporosis of both ankles and C-Section during the last pregnancy in 2011, presented progressively severe bilateral hip pain with onset already in the 12 th gestational week. Imaging of the pelvis and bilateral hips with MRI obtained 6 days after the C-Section demonstrated bilateral bone-marrow edema of the hips. The patient was treated with a monthly single dose of 150 mg ibandronate acid per os, for 3 months and physiotherapy. Repeated MRI performed 5 months postpartum revealed a complete remission of the disease. In contrast to the first onset of transient osteoporosis during the first pregnancy, which was only treated conservatively without bisphosphonates, the remission of the disease and patient's recovery with oral ibandronate therapy showed to be 4 months shorter. This case is unique in literature for both describing the onset of this rare disease twice in the same patient as well as its oral therapeutic approach.

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