Calcium carbonate microcapsules encapsulating biomacromolecules

DNA-mediated morphosynthesis of calcium carbonate particles

“…Finally, the use of DNA did not require stringent conditions, so could be readily extended to the fabrication of other inorganic materials. Also, to our knowledge, there are few reports on the control of DNA on the morphology of CaCO 3 [40,41]. The purpose of the current study was to examine the influence of DNA on the crystallization of CaCO 3 , with the ultimate goal of acquiring an understanding of crystal-DNA interactions and knowledge that could be applied to other systems.…”

Engineering the mechanical and physical properties of organic–inorganic composite microcapsules

“…Biomimetic core-shell structured microcapsules have been developed to encapsulate active ingredients to protect them from an external environment [2][3][4]. Recently, calcium carbonate has attracted considerable attention for making walls of microcapsules due to its biocompatibility and pH triggered release mechanism [5,6]. Thomas et al [7] have utilised a membrane technique to prepare CaCO 3 microcapsules, creating a pseudo water-in-oil-in-water emulsion system to precipitate calcium carbonate at the oil-water interface.…”

Direct encapsulation of proteins into calcium silicate microparticles by water/oil/water interfacial reaction method and their responsive release behaviors

“…In the case of inorganic microparticles, calcium salt derivatives such as calcium phosphates [1][2][3] and calcium carbonate [4] are well-known materials bearing high biocompatibility and bioavailability. Microparticles and nanoparticles of these materials are actively utilized in bioencapsulation [5][6][7][8][9], tissue engineering [1][2][3]10,11] and drug delivery system [1][2][3][4][12][13][14][15]. Calcium silicate is also a potent material for biological and biomedical applications because of its high biocompatibility [16][17][18].…”