Calcium Hydroxylapatite Gel (Radiesse) Injection for the Correction of Postrhinoplasty Contour Deficiencies and Asymmetries

Stupak, Howard D.; Moulthrop, Thomas; Wheatley, Patricia; Tauman, Allison; Johnson, Calvin M.

doi:10.1001/archfaci.9.2.130

Cited by 57 publications

(49 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[5][6][7] Not surprisingly, off label uses of Radiesse have arisen as well. [8][9][10] To our knowledge, no one to date has examined the histologic effects of Radiesse injection at the bony interface. We have now shown that Radiesse is biocompatible and long-lasting subperiosteally.…”

Section: Methods: Fourteen Adult Spraguementioning

confidence: 99%

A preliminary report of percutaneous craniofacial osteoplasty in a rat calvarium

et al. 2013

View full text Add to dashboard Cite

Objectives/Hypothesis To evaluate the potential for injectable, permanent bone augmentation by assessing the biocompatability and bioactivity of subperiosteal hydroxylapatite (Radiesse) deposition in a rat model. Study Design Randomized controlled animal model. Methods Fourteen adult Sprague Dawley rats were injected in the parietal skull with 0.2 ml of hydroxylapatite (10 animals) or 0.2 ml of a carrier gel control (4 animals), using a subperiosteal injection technique on the right and a subcutaneous injection technique on the left. At 1, 3, and 6 months, three rats (1 negative control, 2 variables) were sacrificed and the calvaria were harvested. At 12 months, the remaining five rats were sacrificed. After each harvest, the specimens were processed and then examined under both light and polarized microscopy for new bone growth at the injection sites. Results The inflammatory response was limited with both hydroxylapatite and carrier injections. Injectables were still present 12 months after the injection. New bone formation was only observed when the injection was located deep to a disrupted periosteum The odds of new bone formation was 48.949 times higher (95% confidence intervals CI [2.637, 3759.961]; P = 0.002) with subperiosteal hydroxylapatite injections compared to all other combinations of injection plane and injectable. Conclusions This preliminary report of subperiosteal hydroxylapatite (Radiesse) injection in a rat model has verified the biocompatibility of injectable hydroxylapatite at the bony interface and suggests the potential for new bone formation. Level of Evidence N/A. Laryngoscope, 124:1550–1553, 2014

show abstract

Section: Methods: Fourteen Adult Spraguementioning

confidence: 99%

A preliminary report of percutaneous craniofacial osteoplasty in a rat calvarium

et al. 2013

View full text Add to dashboard Cite

show abstract

“…or decades, soft tissue fillers have been used by plastic surgeons for a variety of facial contouring and correction procedures (1,2). Fillers are a favoured method for wrinkle reduction, scar correction and soft tissue augmentation because they reliably produce good results with few complications (1,2).…”

mentioning

confidence: 99%

“…Fillers are a favoured method for wrinkle reduction, scar correction and soft tissue augmentation because they reliably produce good results with few complications (1,2). The excellent outcomes with filler materials has led to its current surge in popularity in North America.…”

mentioning

confidence: 99%

“…The excellent outcomes with filler materials has led to its current surge in popularity in North America. In addition to using filler countouring for standard procedures, plastic surgeons and dermatologists have begun to consider new uses for soft tissue fillers (1)(2)(3)(4)(5).…”

mentioning

confidence: 99%

“…Soft tissue filler injection has been adopted by several surgeons as a method of correcting deformities of the nose (1)(2)(3)(4)(5). The main indications are correction of remaining asymmetries and contour irregularities in the postoperative rhinoplasty patient (2,4).…”

mentioning

confidence: 99%

See 2 more Smart Citations

Hyaluronic acid used for the correction of nasal deviation in an 18-year-old Middle Eastern man

Piggott¹,

Yazdani²

2011

J Plastic Surgery

View full text Add to dashboard Cite

Survival of diced and block cartilage grafts in combination with injectable calcium hydroxylapatite

et al. 2013

View full text Add to dashboard Cite

show abstract

Calcium Hydroxylapatite Gel (Radiesse) Injection for the Correction of Postrhinoplasty Contour Deficiencies and Asymmetries

Cited by 57 publications

References 18 publications

A preliminary report of percutaneous craniofacial osteoplasty in a rat calvarium

A preliminary report of percutaneous craniofacial osteoplasty in a rat calvarium

Hyaluronic acid used for the correction of nasal deviation in an 18-year-old Middle Eastern man

Survival of diced and block cartilage grafts in combination with injectable calcium hydroxylapatite

Contact Info

Product

Resources

About