2004
DOI: 10.1089/cpt.2004.2.180
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Calcium Mobilization in Freeze-Dried Human Platelets

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Cited by 8 publications
(3 citation statements)
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“…Although there are still some arguments about the exact mechanisms of Ca 2+ on NHE1 activation, it is clear that calcium is very important in thrombin‐induced pH i regulation 31,44 . Previous studies in our laboratory have shown that rehydrated PLTs have a decreased calcium response upon stimulation with thrombin 45 . We suggest that the decreased alkalization response to thrombin in rehydrated PLTs can be attributed to a decrease in intracellular calcium mobilization.…”
Section: Discussionmentioning
confidence: 73%
“…Although there are still some arguments about the exact mechanisms of Ca 2+ on NHE1 activation, it is clear that calcium is very important in thrombin‐induced pH i regulation 31,44 . Previous studies in our laboratory have shown that rehydrated PLTs have a decreased calcium response upon stimulation with thrombin 45 . We suggest that the decreased alkalization response to thrombin in rehydrated PLTs can be attributed to a decrease in intracellular calcium mobilization.…”
Section: Discussionmentioning
confidence: 73%
“…Auh et al 2004). Several groups have tried to use trehalose to preserve nucleated cells in the dry state, and it became apparent that adding trehalose alone was not sufficient, as I will describe below.…”
Section: Discussionmentioning
confidence: 99%
“…Auh et al . ). Several groups have tried to use trehalose to preserve nucleated cells in the dry state, and it became apparent that adding trehalose alone was not sufficient (reviewed in Crowe ).…”
mentioning
confidence: 97%