A mine dump truck is exposed to heavy load and harsh working environment. When the truck passes over the road bumps, it will cause the body to tilt and the tires to "jump off the ground" (JOTG), which will affect the stability and safety of the truck, and will cause impact damage to the body and suspension system. To avoid this situation, a kind of Novel Single-side Coupling Hydro-pneumatic Suspension (NSCHs) is presented. NSCHs consists of two cylinders in parallel, which are connected to the accumulator by rubber pipes and mounted on the same side of the dump truck. Theoretical analysis and experimental research were respectively carried out under the road and loading experimental condition. The experimental results show that compared to the conventional single cylinder hydro-pneumatic suspension, under the loading experiment condition, the maximum overshoot pressure of the NSCHs was reduced by 0.4 MPa and the impact oscillation time was shortened by 4.13 s, which plays the effective role in reducing vibration and absorbing energy. Further, it is found that the two cylinders are coupled during the working process, and the NSCHs system can achieve uniform loading and displacement compensation, thus the novel dump truck can avoid the occurrence of the JOTG phenomenon.