A simple modification of the empirical model of Hombourger (HEMP) [1998 J. Phys. B 31 3693] is proposed with ionic and relativistic corrections in it. The modified HEMP (MHEMP) model has been applied to 11 H- and He-like ionic targets with a wide range of atomic numbers Z = 5–92 to calculate the electron impact single ionization (EISI) cross sections. MHEMP with a single set of parameter values is found to describe excellently the experimental EISI cross sections of B4+, C4+, N6+, O7+, Ne8+, Mo41+, Dy65+, Au78+, Bi82+, U90+ and U91+ up to an incident energy of about 460 keV.