Calculations regarding cell metabolism stimulation using photons in the visible wavelength range

Abstract

Abstract:The driving force behind the complex system of metabolism is based on the efficient use of potential differences. An intact biological system has a dynamic equilibrium in which the cellular biochemical reactions are in a pseudo-stationary state. The equilibrium can be manipulated by external effects such as, temperature changes brought about radiation absorption. Hot spots can be induced by the absorption of photons in strongly absorbing areas within the tissue or the sub-cellular components. Simulation calculations were carried out and utilized for selective manipulation within a spatially limited target volume, using simplified parameters for observation of the model. A good correlation was established between the results of the simulation and the measuring data based on absorption and scattering values for fibroblasts and liver tissue. Relevant biochemical causes of the stimulation effects at cellular level are considered in the discussion. The effect of stimulation with a laser on tissue such as cartilage, using a simplified two-dimensional tissue model system which is mainly supplied by diffusion processes, is discussed here with a view to its use in medicine.

Light-emitting diode effects on combined decellularization of tracheae. A novel approach to obtain biological scaffolds

“…As well as that, they show that the interactions of the electromagnetic waves with the biological tissue cause the cells to warm up a little, including their mitochondrial membrane, leading to oxidative stress and triggering biochemical reactions that speed up the metabolism by increasing oxygen consumption 32 . A cell is usually able to overcome the effects of stress provided that the disturbances of the redox balance are small, restoring normal intracellular balance with positive stimulatory effects on the cells; largerscale disturbances, however, may be lethal to the cells [17][18][19] .…”

“…More recent in vitro studies show that the action of low-intensity Laser can also be applied to repair and regenerate cartilages due to the biostimulation in the production of the cartilage matrix 32 . As well as that, they show that the interactions of the electromagnetic waves with the biological tissue cause the cells to warm up a little, including their mitochondrial membrane, leading to oxidative stress and triggering biochemical reactions that speed up the metabolism by increasing oxygen consumption 32 .…”

The effect of an Er,Cr:YSGG laser on external adaptation of healthy and decayed cavities

“…The first challenge to the adhesive interface during adhesive restorative procedures is represented by the resistance to the stresses generated by polymerization shrinkage, specifically during the curing of polymeric materials [6][7][8]. Therefore, it is important that the immediate bond strength should be strong enough to withstand these stresses.…”

Biostimulatory effects of low-level laser therapy on epithelial cells and gingival fibroblasts treated with zoledronic acid

“…In vitro and in vivo studies have demonstrated that LLLT causes biostimulatory effects on different cell types, characterized by increase in cell proliferation, metabolism, migration, and protein and gene expression [14][15][16]. It has also been shown that specific LLLT can penetrate tissues, promoting local biostimulation [17][18][19].…”