Please cite this article as: Han, Y., Liu, W., Bretz, F., Wan, F., Yang, P., Statistical calibration and exact one-sided simultaneous tolerance intervals for polynomial regression. J. Statist. Plann. Inference (2015), http://dx.doi.org/10.1016/j.jspi. 2015.07.005 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.