Calibration Transfer in near Infrared Analysis of Liquids and Solids

Wang, Qian; DeJesus, Stephen T.; Conzen, J.-P.; Schmidt, Angela; Weiler, Helmut

doi:10.1255/jnirs.194

Cited by 8 publications

(4 citation statements)

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“…In case of transfer of NIR applications between similar instruments of the same make [16,17], direct transfer is not always successful. Transfer by bias adjustment, as described in this study, can be applied for quantitative applications, which requires at least an accurate and stable wavelength-axis by construction, combined with bias adjustments that are dependent on the calibration [18,19].…”

Section: Resultsmentioning

confidence: 99%

Assessing the transfer of quantitative NIR calibrations from a spectrometer to another one

Ulmschneider

Pénigault

2000

Analusis

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Abstract. Many factors account for the optical differences between two near-infrared (NIR) spectrometers of the same make and type. The use of two NIR spectrometers may involve different calibrations, that can be transferred only with additional work, like bias adjustments, other sample measurements, model recalculations, conversion of spectral data, etc. In most cases direct transfers of the applications are not possible. In this study the feasibility of a calibration transfer between FOSS/NIRSystems NIR spectrometers was checked. The set of multivariate calibrations for a non-invasive identity testing and a direct determination of the water content in ceftriaxone disodium salt sterile (Rocephin ® ) and in a preparation containing tenoxicam active substance (Tilcotil ® ) filled in vials, was transferred from one spectrometer to another. Separate bias adjustments were calculated for each calibration to fit the spectral data collected on both instruments. These considerations define a practicable procedure to transfer quantitative NIR applications with a reasonable amount of additional work.

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Section: Resultsmentioning

confidence: 99%

Assessing the transfer of quantitative NIR calibrations from a spectrometer to another one

Ulmschneider

Pénigault

2000

Analusis

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“…HPLC or Karl Fisher titration. Also, calibrations may need to be updated when suppliers change, or when the process is modified (Candolfi & Massart 2000;Wang et al 1998).…”

Section: Theory and Characteristics Of Nir Spectroscopymentioning

confidence: 99%

Near infrared spectroscopy in the development of solid dosage forms

Räsänen

Sandler

2007

Journal of Pharmacy and Pharmacology

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The use of near infrared (NIR) spectroscopy has rapidly grown partly due to demands of process analytical applications in the pharmaceutical industry. Furthermore, newest regulatory guidelines have advanced the increase of the use of NIR technologies. The non-destructive and non-invasive nature of measurements makes NIR a powerful tool in characterization of pharmaceutical solids. These benefits among others often make NIR advantageous over traditional analytical methods. However, in addition to NIR, a wide variety of other tools are naturally also available for analysis in pharmaceutical development and manufacturing, and those can often be more suitable for a given application. The versatility and rapidness of NIR will ensure its contribution to increased process understanding, better process control and improved quality of drug products. This review concentrates on the use of NIR spectroscopy from a process research perspective and highlights recent applications in the field.

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“…Accurate calibrations are most useful when comparing measurements from several instruments, such as during transfer of calibrations between instruments. [8][9][10][11] Thus, we anticipate these results will be most useful in transferring multivariate calibrations between instruments. We expect they will also be useful wherever accurate measurement of wavelength is desired, such as in monitoring tunable diode lasers.…”

Section: Introductionmentioning

confidence: 98%

Accurate and Precise Wavelength Calibration for Wide Bandwidth Array Spectrometers

et al. 2008

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Calibrating the wavelength scale of an array spectrometer typically involves measurements of lines at well-known wavelengths from a calibration lamp such as a mercury-argon source. This process is relatively straightforward when the lines are well separated, relative to the bandwidth of the spectrometer. When the spectrometer's bandwidth is large, compared with the distance between calibration wavelengths, it becomes increasingly difficult to accurately locate lines in the calibration spectrum. Even calibrations for instruments with a modest bandwidth of 12 nm can be difficult. Here we present results from a simple approach to improve the accuracy of wavelength calibration for an instrument with a large bandwidth (12 nm, center-to-center pixel spacing 3.3 nm). A monochromator has been used to filter the source so that each calibration line can be measured separately. For ten spectrometers, we were able to achieve accuracy better than 0.12 nm, or 0.09 nm on average; this is less than 3% of the pixel spacing. We anticipate this approach will be useful for improving the accuracy of measurements on array spectrometers and particularly in transferring multivariate calibrations between instruments.

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Calibration Transfer in near Infrared Analysis of Liquids and Solids

Cited by 8 publications

References 0 publications

Assessing the transfer of quantitative NIR calibrations from a spectrometer to another one

Assessing the transfer of quantitative NIR calibrations from a spectrometer to another one

Near infrared spectroscopy in the development of solid dosage forms

Accurate and Precise Wavelength Calibration for Wide Bandwidth Array Spectrometers

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