Calicivirus infection in human immunodeficiency virus seropositive children and adults

Rodríguez-Guillén, L.; Vizzi, Esmeralda; Alcalá, Ana C.; Pujol, Flor H.; Liprandi, Ferdinando; Ludert, Juan E.

doi:10.1016/j.jcv.2004.09.031

Cited by 24 publications

(28 citation statements)

References 32 publications

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“…Previous studies indicated that human caliciviruses were detected more frequently in HIV-infected children compared to HIV-uninfected children [28]. In a Kenyan study, SaV was detected in 5.7% (6/105) of HIV-infected children with five different genotypes detected [6].…”

Section: Discussionmentioning

confidence: 86%

Sapovirus prevalence in children less than five years of age hospitalised for diarrhoeal disease in South Africa, 2009–2013

Page¹,

Groome²,

Murray³

et al. 2016

Journal of Clinical Virology

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Word count abstract: 248Word count article: 2500 2 Highlights:Sapovirus was detected in children hospitalised with acute diarrhoea and in deaths Sapoviruses are common in males, in the second year of life during summer and autumn Factors associated with SaV detection included overcrowding and norovirus infectionsHIV-infected children with SaV had bloody stool and poor access to sanitation Abstract:Background: Although sapovirus (SaV) has been detected in 2.2% to 12.7% of

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Section: Discussionmentioning

confidence: 86%

Sapovirus prevalence in children less than five years of age hospitalised for diarrhoeal disease in South Africa, 2009–2013

Page¹,

Groome²,

Murray³

et al. 2016

Journal of Clinical Virology

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“…Although most norovirus infections are acute and self-limiting, the infection can become chronic in (i) solid-organ and hematopoietic stem cell transplant recipients (2-4), (ii) patients undergoing chemotherapy (3,5,6), and patients with immunodeficiencies, including those caused by HIV infection (7)(8)(9)(10). Prolonged norovirus infection can also be observed in young children (11) and the elderly (12,13).…”

mentioning

confidence: 99%

Treatment with a Nucleoside Polymerase Inhibitor Reduces Shedding of Murine Norovirus in Stool to Undetectable Levels without Emergence of Drug-Resistant Variants

Rocha‐Pereira

Dycke

Neyts

2016

Antimicrob Agents Chemother

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Prolonged norovirus shedding may occur in certain patients, such as organ transplant recipients. We established a mouse model for persistent norovirus infection (using the mouse norovirus MNV.CR6 strain). The nucleoside viral polymerase inhibitor 2=-C-methylcytidine (2CMC), but not favipiravir (T-705), reduced viral shedding to undetectable levels. Viral rebound was observed after stopping treatment, which was again effectively controlled by treatment with 2CMC. No drugresistant variants emerged.

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“…Caliciviruses infect people of all ages and constitute important etiological agents for diarrhea, while noroviruses are the main causative agents of non-bacterial epidemic acute gastroenteritis, worldwide 5 . Although uncommon, infection by gastroenteric viruses can generally also occur among adults, especially elderly and immunosuppressed individuals [6][7][8] . Acute gastroenteritis due to astrovirus has been reported in immunosuppressed (transplanted or HIV-seropositive) adults and children 9,25 .…”

Section: Resultsmentioning

confidence: 99%

“…Among the more than twenty known gastroenteric viruses, the most important etiological agents of acute gastroenteritis are rotaviruses, enteric adenoviruses, astroviruses and human caliciviruses [3][4][5] . Elderly and immunosuppressed individuals are among those with the highest susceptibility to infection and reinfection by gastroenteric viruses [6][7][8][9] . It is also believed that pregnant women and HIVseropositive individuals are more vulnerable to viral infections than is the general population 7,10 .…”

Section: Introductionmentioning

confidence: 99%

“…Elderly and immunosuppressed individuals are among those with the highest susceptibility to infection and reinfection by gastroenteric viruses [6][7][8][9] . It is also believed that pregnant women and HIVseropositive individuals are more vulnerable to viral infections than is the general population 7,10 . We decided to conduct this study because of the epidemiological importance of viral gastroenteritis and the assumption that pregnant women, whether HIV-seropositive or not, could constitute a group potentially at risk of viral infection and the development of gastroenteric disease, and also due to the scarcity of information on the incidence of gastroenteric viruses among the adult female population Our study presents novel data on gastroenteric viruses (astroviruses and caliciviruses) among adult pregnant women (either HIV-seropositive or not) from the central-western region of Brazil.…”

Section: Introductionmentioning

confidence: 99%

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Gastroenteric virus detection in fecal samples from women in Goiânia, State of Goiás, Brazil

Ferreira

Borges

Fiaccadori

et al. 2010

Rev. Soc. Bras. Med. Trop.

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Introduction: This was a prospective study that included women seen in the obstetrics and gynecology sector of Hospital das Clínicas, Federal University of Goiás, in Goiânia, State of Goiás, with the aim of detecting rotaviruses, adenoviruses, caliciviruses and astroviruses. Eighty-four women participated in the study and from these, 314 fecal samples were collected. Out of all of the women, 29 were seropositive for HIV and 55 were seronegative, and 45 and 39 were pregnant and non-pregnant, respectively. Methods: Fecal samples were collected from each woman once every two months over the period from July 2006 to June 2007, and they were screened for rotaviruses by means of polyacrylamide gel electrophoresis and immunoenzymatic assays, for caliciviruses and astroviruses by means of RT-PCR and for adenovirus by means of immunoenzymatic assays. The astroviruses were genotyped using nested PCR. Results: Among the 84 patients, 19 (22.6%) were positive for either calicivirus (14/19) or astrovirus (6/19), while one women was positive for both viruses in fecal samples collected on different occasions. Most of the positive samples were collected during the months of July and August (astrovirus) and September and October (calicivirus). None of the samples analyzed was positive for rotavirus or adenovirus. Gastroenteric viruses were detected in 13/19 (68.4%) of the pregnant women, whether HIV-seropositive or not. Conclusions: The results from the present study showed that neither pregnancy nor HIV-seropositive status among the women increased the risk of infection by any of the gastroenteric viruses studied. This study presents data on gastroenteric virus detection among pregnant and/or HIV-positive women.

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Calicivirus infection in human immunodeficiency virus seropositive children and adults

Cited by 24 publications

References 32 publications

Sapovirus prevalence in children less than five years of age hospitalised for diarrhoeal disease in South Africa, 2009–2013

Sapovirus prevalence in children less than five years of age hospitalised for diarrhoeal disease in South Africa, 2009–2013

Treatment with a Nucleoside Polymerase Inhibitor Reduces Shedding of Murine Norovirus in Stool to Undetectable Levels without Emergence of Drug-Resistant Variants

Gastroenteric virus detection in fecal samples from women in Goiânia, State of Goiás, Brazil

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