Sapovirus prevalence in children less than five years of age hospitalised for diarrhoeal disease in South Africa, 2009–2013

Page, Nicola; Groome, Michelle; Murray, Tanya Y.; Nadan, Sandrama; Netshikweta, Rembuluwani; Keddy, Karen H.; Poonsamy, Bhavani; Moyes, Jocelyn; Walaza, Sibongile; Kahn, Kathleen; Kuonza, Lazarus; Taylor, Maureen B.; Madhi, Shabir А.; Cohen, Cheryl

doi:10.1016/j.jcv.2016.03.013

Cited by 37 publications

(38 citation statements)

References 29 publications

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“…Co-infections included adenovirus (AdV), astrovirus, bocavirus, norovirus (NoV) GI, NoV GII or rotavirus (RV) [21]. The most frequent co-infection was AdV (43%), followed by NoV GII and RV in 21% of specimens each.…”

Section: Resultsmentioning

confidence: 99%

“…As part of the ongoing Rotavirus Sentinel Surveillance Programme (RSSP), all specimens were screened for SaV and other enteric viruses [21]. Specimens were collected from children younger than six years old who were hospitalised with gastroenteritis in four provinces of SA (GP; KwaZulu Natal, KZN; Mpumalanga, MP and the Western Cape, WC).…”

Section: Specimen Collection and Processingmentioning

confidence: 99%

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Diverse sapovirus genotypes identified in children hospitalised with gastroenteritis in selected regions of South Africa

Murray

Nadan

Page³

et al. 2016

Journal of Clinical Virology

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Section: Resultsmentioning

confidence: 99%

Section: Specimen Collection and Processingmentioning

confidence: 99%

Diverse sapovirus genotypes identified in children hospitalised with gastroenteritis in selected regions of South Africa

Murray

Nadan

Page³

et al. 2016

Journal of Clinical Virology

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“…In Brazil, 18.6% of fecal samples and 36.3% of nasopharyngeal swab samples were detected SaV‐positive from 102 hospitalized children with symptoms of acute gastroenteritis . More importantly, it was reported that 11.4% (9 of 79) diarrheal deaths of children were caused by SaV infection in South Africa …”

Section: Discussionmentioning

confidence: 99%

Prevalence and genetic diversity of human sapovirus associated with sporadic acute gastroenteritis in South China from 2013 to 2017

Xue¹,

Cai²,

Zhang³

et al. 2019

Journal of Medical Virology

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Human sapovirus (SaV) is an important viral agent for acute diarrhea worldwide, but timely prevalence data of human SaV in South China are still lacking. In this study, a 4‐year surveillance was conducted to characterize the prevalence and genetic characteristics of the circulating SaV associated with sporadic diarrhea in South China. From November 2013 to October 2017, 569 fecal samples from patients with acute diarrhea were collected. SaV was detected in 11 samples with a positive rate of 1.93%. Three human genogroups of GI, GII, and GIV were identified, including five GI.1 strains, three GI.2 strains, one GI.3 strain, one GII.8 strain, and one GIV strain. Furthermore, multiple alignments of complete capsid protein VP1 genes of five local GI.1 strains and other available GI.1 strains in GenBank were performed. Average pairwise identities were calculated at 95.33% and 99.36% at nucleotide and amino acid levels, and only six variable amino acid sites were found during its 36‐years’ evolution process. GI.1 strains could be further phylogenetically divided into four clusters with an approximate temporal evolution pattern, and local strains belonged to Cluster‐d with other four strains from China and Japan. In summary, SaV was identified as an etiological agent responsible for sporadic gastroenteritis in Guangzhou with a low prevalence rate as in other Chinese cities, but its high genetic diversity suggested the necessity of continuous SaV surveillance in the future.

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“…Sapovirus is a member of the Caliciviridae family that worldwide is responsible for 2.2–12.7% of gastroenteritis and has been reported in more than 35 countries [3–5]. Incubation period is from 1 to 4 days, and there is a median of 6 days of symptoms.…”

Section: Discussionmentioning

confidence: 99%

“…Sapovirus has been studied significantly less than other more common Caliciviridae like norovirus. The clinical presentation of nonbloody diarrhea and vomiting is generally milder than seen with rotavirus or norovirus, but hospitalizations and deaths have been reported [5], particularly in rural areas without running water and in immunocompromised children [3]. PCR assays are the best current method for detection of viral strains [7].…”

Section: Discussionmentioning

confidence: 99%

Sapovirus Gastroenteritis in Young Children Presenting as Distal Small Bowel Obstruction: A Report of 2 Cases and Literature Review

Model

Burnweit

2016

Case Reports in Surgery

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Abdominal pain and distention in children are commonly encountered problems in the pediatric emergency room. The majority of complaints are found to be due to benign entities such as gastroenteritis and constipation. What confounds these diagnoses is that young children often deliver a challenging and unreliable exam. Thus, it often becomes exceedingly problematic to differentiate these benign conditions from surgical conditions requiring prompt attention including small or large bowel obstruction, volvulus, and appendicitis. The cases highlight Sapovirus as a cause of severe abdominal distention and vomiting in children and this report is the first to describe and demonstrate the impressive radiologic findings that may be associated with this infection. Surgeons should heed this information and hesitate to emergently operate on similar children.

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Sapovirus prevalence in children less than five years of age hospitalised for diarrhoeal disease in South Africa, 2009–2013

Cited by 37 publications

References 29 publications

Diverse sapovirus genotypes identified in children hospitalised with gastroenteritis in selected regions of South Africa

Diverse sapovirus genotypes identified in children hospitalised with gastroenteritis in selected regions of South Africa

Prevalence and genetic diversity of human sapovirus associated with sporadic acute gastroenteritis in South China from 2013 to 2017

Sapovirus Gastroenteritis in Young Children Presenting as Distal Small Bowel Obstruction: A Report of 2 Cases and Literature Review

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