“…Several recently published studies demonstrate the effect of physical activity, disease activity, corticosteroids, especially before puberty, nutrition, sun exposure, vitamin D, growth, and smoking on the quality of BMD in children with JIA. 5,7,10,12,13 Current knowledge on bone health in children with JIA has established that a sedentary lifestyle contributes to secondary impairments in bone health, muscular fitness, and functional limitations, despite advances in pharmacologic treatment of inflammatory diseases. 13 In a review study from 2007, 8 randomized intervention studies showed beneficial effects from weight-bearing exercise for 8 to 16 weeks, 2 and 3 times a week.…”