Can stability of visual fixation be a measure for disability in multiple sclerosis?

Serra, Alessandro; Petzold, Axel

doi:10.1177/1352458520903296

Cited by 3 publications

(2 citation statements)

References 12 publications

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“…In this context, it is worth mentioning that recent works indicate the visuomotor system might be applied to control the motor disability in MS by monitoring fixational microsaccades (Serra & Petzold, 2020 ; Sheehy et al., 2020 ).…”

Section: Multiple Sclerosismentioning

confidence: 99%

Optical coherence tomography monitoring and diagnosing retinal changes in multiple sclerosis

et al. 2021

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This study explores the use of optical coherence tomography (OCT) to monitor and diagnose multiple sclerosis (MS). The analysis of reduced total macular volume and peripapillary retinal nerve fiber layer thinning are shown. The severity of these defects increases as MS progresses, reflecting the progressive degeneration of nerve fibers and retinal ganglion cells. The OCT parameters are noninvasive, sensitive indicators that can be used to assess the progression of neurodegeneration and inflammation in MS.

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Section: Multiple Sclerosismentioning

confidence: 99%

Optical coherence tomography monitoring and diagnosing retinal changes in multiple sclerosis

et al. 2021

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“…Worthy of mention in this context are the recent works showing that the visuomotor system could be used to track motor dysfunction in MS through the monitoring of fixational microsaccades [68,69] .…”

Section: Multiple Sclerosismentioning

confidence: 99%

Inflammation in the anterior visual pathway in multiple sclerosis: what do the animal models teach us?

Cordano¹,

Ramos²,

Arnow³

et al. 2020

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A provocative and overly reductive mantra is that "the back of the eye is the front of the brain". Retinal imaging techniques that take advantage of this "window" to the central nervous system can provide valuable information regarding injury to the nervous system with relative ease and with a limited burden to patients. The retina develops embryonically as part of the neuroectoderm, is made up principally of neurons and their supporting cells, and is synaptically tied to the central nervous system (CNS). This has led to significant interest in using retinal health as a biomarker for brain health-given the relatively limited accessibility of brain tissue in chronic neurodegenerative diseases that progress over decades. The retina is not truly part of the CNS, and as with much of brain imagingthe grounds for asserting the pathological specificity of retinal imaging is limited. Biophotonics-based methods such as optical coherence tomography indirectly provide an opportunity to evaluate retinal neurodegeneration, while autopsy studies, histology and immunohistochemistry predominate as the methods that collect direct pathological data. Our understanding of pathological retinal lesions characteristic of demyelinating diseases, specifically diseases showing anterior visual pathway involvement, has grown significantly in recent years.

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Diagnosis and classification of optic neuritis

Petzold

Fraser²,

Abegg³

et al. 2022

The Lancet Neurology

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131

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Can stability of visual fixation be a measure for disability in multiple sclerosis?

Cited by 3 publications

References 12 publications

Optical coherence tomography monitoring and diagnosing retinal changes in multiple sclerosis

Optical coherence tomography monitoring and diagnosing retinal changes in multiple sclerosis

Inflammation in the anterior visual pathway in multiple sclerosis: what do the animal models teach us?

Diagnosis and classification of optic neuritis

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