This article analyzes the abundance and composition of marine litter in the Gulf of Sant Jordi (Catalonia, Spain). Marine litter was removed from the sea by a fishing trawler operating from the port of L’Ametlla de Mar; 56 hauls were performed between July and September 2018. The marine litter was classified following UNEP/IOC Guidelines on Survey and Monitoring of Marine Litter and EU MSFD Technical Group on Marine Litter Joint List, with a total of 2691 items collected and an average number by haul of 48 (SD 28.24). The density was 130 items km−2 but with significant differences according to trawling depth: 192 items km−2 (≤100 m) and 71.5 items km−2 (>100 m). As expected, plastic was the most commonly found material, comprising almost 80% of the total. The relative presence of plastics declined as trawling depth increased. An alarmingly high amount of sanitary waste was found. Further studies are necessary to compare summer results with those of smaller seasonal populations and to analyze what happens to sanitary waste.