Cancer and Germ Cells

Abstract

Background: Era of contraception, abortions, [20th, 21st centuries] implemented as family welfare schemes witnessed, increased global incidence of cancer, tumors, neoplasm and mortality. Objectives: Altruistic association of contraception [if any], with increasing cancer, tumor was sought after. Methods: In 2012, retrospective analysis of, prevalence of cancer, tumor in 350 patients of 20-35 years, 35-50 years, >50 years age groups, from data collected by convenient, stratified random sampling, from different geographical locations, between 2002-2012 and its association with presence, absence of contraception, abortion was undertaken; simultaneously, serum estrogen levels obtained from 105 patients, were also analyzed. From 1983-2012 clinical practice, 212 patients treated for different types of neoplasm namely breast cancer, prostate cancer, cancer cervix and benign prostatic hyperplasia were randomly allotted to the above 3 age groups and the data were analyzed for association with contraception status and possible significance. Results: 6 fold increase in cancer incidence was seen in contraceptive users among >50 years with a p value of <0.0005. Contraception was associated with 4-7 fold increase in tumor prevalence among >35->50 years with a p value of <0.0005. Endogenous estrogen had decreased to ~5-8 pg in 61% of contraceptive users with a p value of <0.0005; after hysterectomy endogenous estrogen values up to ~0.4 pg were seen. Cholesterol deprived diet, due to decreased synthesis of endogenous estrogen:androgen also was associated with 50% increase in tumor, cancer in youth without contraception. Estrogen receptors were positive in well differentiated cancers of breast, associated with reduced levels of endogenous estrogen among contraceptive users, suggesting estrogen receptor positivity could be a compensatory phenomenon; anaplastic tumors did not exhibit estrogen receptor positivity. 10-20 fold increase in breast cancer was seen among 20->50 years, in contraceptive users with a p value of <0.0005; 20-30 fold increase in prostate cancer was seen among 35->50 years, in contraceptive users with a p value of <0.0005; cancer of the cervix had increased 20-40 fold, among 20-70 years, in contraceptive users with a p value of <0.0005. Conclusion: Concept is acquired contraception preventing traversal of normal path by germ cells with resultant smashed destruction of germ cells, consequent reduced endogenous estrogen:androgen surveillance, leading to agonizing faults of cellular genomic repertoire, uncontrolled multiplication E. J. V. Samuel et al. 607 preceded by no differentiation of cell cycle, metabolism, resulting in soaringly high incidence of cancers including breast, prostate and uterine cervix in both life partners. Increased estrogen receptors:androgen receptors in breast, prostate well differentiated cancers respectively are, probably a compensatory rise, secondary to the sudden artificially acquired contraception resulting in significant reduction of endogenous germ cell hormones in contraceptive us...

Oseltamevir Helps Cure COVID 19, Corona Pandemic Carried by Global Abortion/Contraception, Global Blood/Necrotic Tissue Environmental Pollution; Guaranteed Corona Elimination by Implementing Many Childbirth per Family [Earth Bus Fare/Ticket]; Contraception Reversal; Abolition of Global Contraception [One Child Policy, Small Family Norms], Abortion [Jumping off Cliff to Fly-Marred Science]&lt;br/&gt;—Retrospective Analysis

“…Oestrogen being a hormone, is directly secreted into the blood, circulates in the blood, governs [surveillance] every cell metabolism, [cell growth-differentiation-controlled multiplication-degeneration-programmed cell death (apoptosis)-new cell formation in 48 -72 hours] in every tissue, [anabolism] thus protects [6] every cell from carcinogenesis, [cell growth with no differentiation followed by uncontrolled multiplication-due to poor hormonal surveillance] [7] increases vasodilatation by enhancing nitric oxide production, [8] inhibits atherogenesis (degenerative pathology), decreases thrombogenecity and reduces incidence of myocardial infarction in premenopausal women, endogenous estrogen helps in decreasing progression of dementia, endogenous oestrogen governs secondary sexual dimorphism, hence obesity does not ensue.…”