Câncer de Mama em Mulheres Jovens: Análise de 12.689 Casos

Pinheiro, Aline Barros; Lauter, Dagmar Scholl; Medeiros, Giselle Coutinho; Cardozo, Isabella Ribeiro; Menezes, Letícia Mattos; Souza, Raysa Messias Barreto de; Abrahão, Karen de Souza; Casado, Letícia; Bergmann, Anke; Thuler, Luiz Cláudio Santos

doi:10.32635/2176-9745.rbc.2013v59n3.500

Cited by 20 publications

(20 citation statements)

References 15 publications

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“…In 2013, a national study carried out with more than 12,000 breast cancer patients under 40 years of age (mean age 36 years) also found a higher prevalence of IIA staging 1 . Similar data were presented by Stival et al, who detected a higher frequency of IIA and IIB tumors in patients aged between 40 and 50 years, with no significant differences in individuals over 50 years 20 . The time between visiting the service and surgical treatment was longer than that recommended by the Ministry of Health (60 days) 21 and may be associated with the disproportion between the demand for care and the organizational structure of the service.…”

Section: Discussionmentioning

confidence: 99%

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Tumor biological profile of patients up to 50 years of age in a countryside city of São Paulo

et al. 2021

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Introduction: In Brazil, breast cancer screening is not performed in young women. However, although less frequent, the disease is generally more aggressive in this age group, with worse prognosis and refractoriness to treatment. Thus, the identification of specific subtypes by immunohistochemistry can help improve the effectiveness of treatments. Objectives: To evaluate the biological characteristics of breast tumors in patients under 50 years. Methods: This is an observational, longitudinal, retrospective study, based on data collected from medical records of the Hospital do Câncer de Franca, from January 2015 to February 2018. Results: The most frequent biological subtype was luminal B (42.5%), and the mean age of the women was 43.6 years. The most prevalent clinical staging was IIA (31%). Mastectomy with axillary drainage was the most used surgical treatment. A positive correlation was found between biological profiles and sociodemographic data, with a predominance of the luminal B subtype in women under 40 years and luminal A in those between 41 and 50 years. The mean tumor size was 4.2 cm, being larger in older and white patients. In multiparous women, the subtypes HER2 and luminal A and B stood out. Conclusion: Luminal B and luminal A biological profiles, as well as staging II and III, were the most prevalent. Mastectomy and axillary drainage were the most common surgical treatments. The employment of these procedures should be reviewed by the service in order to improve the quality of life of the patients treated, favoring the expansion of primary conservative surgeries or post-neoadjuvant chemotherapy.

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Section: Discussionmentioning

confidence: 99%

“…Currently, breast cancer is the subject of many scientific discussions about screening and treatment due to its high incidence and for being the main cause of cancer death among women in Brazil and worldwide 1 . The worldwide incidence is approximately 1.7 million, representing the second most common type of cancer in women 2 .…”

Section: Introductionmentioning

confidence: 99%

Tumor biological profile of patients up to 50 years of age in a countryside city of São Paulo

et al. 2021

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“…Uma etapa primordial no diagnóstico responsável por definir as modalidades do tratamento oncológico é o estadiamento 20 . Quando notificado, observou-se que os estádios frequentes eram o III e IV, referentes a tumores com disseminação local extensa e tumores com metástases a distância, respectivamente 21 .…”

Section: Discussionunclassified

“…Tendo como referência os cânceres mais prevalentes nessa população, estudos 22,23 revelam que os estádios I e II foram os mais observados nos casos de neoplasia da mama e os estádios III e IV para a neoplasia de estômago 24,25 . Em contrapartida, um estudo 21 observou aumento de casos com estadiamento clínico avançado e presença de metástases para o câncer de mama. Diferente dos países de primeiro mundo no qual o diagnóstico para o câncer de mama tende a ser precoce, no Brasil 40% a 60% dos casos pertencem aos estádios III e IV 22 .…”

Section: Discussionunclassified

Análise de Prescrições Médicas de Pacientes Oncológicos / Analysis of Medical Prescriptions of Cancer Patients

Oliveira¹,

Oliveira²,

Silva³

et al. 2021

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RESUMOIntrodução: Uma das etapas mais importantes no processo da terapia antineoplásica é a avaliação da prescrição médica, capaz de reduzir erros de medicação, aumentar a efetividade e minimizar os riscos da farmacoterapia. Objetivo: Consiste na análise das intervenções farmacêuticas sobre a ocorrência de problemas relacionados aos medicamentos por meio da avaliação das prescrições. Além disso, buscou identificar a aceitabilidade e adesão da equipe frente às intervenções propostas. Método: Foram analisadas 100 prescrições divididas em duas fases. A primeira metade serviu para identificar a presença de problemas e sua prevalência. A segunda metade foi analisada com o intuito de identificar se houve persistência ou melhora dos problemas identificados após a intervenção farmacêutica. A aceitabilidade e adesão foram avaliadas no decorrer do estudo e através dos resultados obtidos. Resultados: Nas duas fases, houve predominância de prescrições do sexo feminino e o câncer de mama e de estômago foram os diagnósticos prevalentes. A maioria dos problemas identificados nas prescrições estavam relacionados ao volume do diluente e ao tempo de infusão dos medicamentos, aspectos responsáveis pela maioria das intervenções farmacêuticas. O estudo apresentou elevado índice de aceitabilidade das intervenções pela equipe médica nas duas fases, entretanto não houve adesão. Conclusão: O número de problemas relacionados aos medicamentos permanece frequente mesmo com as intervenções e os materiais elaborados nesta pesquisa, refletindo a importância da continuidade de trabalhos com a finalidade de prevenir erros e auxiliar outros profissionais de saúde.

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“…Breast cancer (BC) is the most common malignant neoplasm among women in Brazil and in the rest of the globe, accounting for 23% of all cancer cases worldwide 1,2 . Several risk factors have already been established, including endogenous and environmental factors.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of clinical, pathological and epidemiological profile of patients with breast cancer in the microregion of Lavras – MG

et al. 2023

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Introduction: Breast cancer is associated with high frequency and mortality in Brazilian women. There have been limited studies portraying the characteristics of breast cancer cases in the countryside of the state of Minas Gerais for a long period of time, a fact that will allow us to better understand the epidemiology of these tumors. This descriptive study aims to analyze the epidemiology and clinical features of patients with breast cancer treated at a public health service facility in Lavras, MG. Methods: This is a transversal study with 299 women diagnosed with breast cancer between 2002 and 2022, based on data collection from medical records and subsequent descriptive analysis. Results: There were a total of 317 cases, and 299 were eligible for the study. The mean age at diagnosis was 54.2 years, and 36.1% of the patients were under 50 years old at diagnosis. Positive family history was found in 17.0% of the patients. The diagnosis was made by clinical alteration detected on physical examination in 71.5% of cases, and lump was the most frequent type of lesion (89.0%). Invasive carcinoma was 93.1% of the cases, and the mean tumor size was 28.6 mm. The average time between first medical appointment and diagnosis was 63.2 days, and between diagnosis and beginning of treatment was 39.6 days. Conclusions: This study showed that a significant number of cases occurred in women outside the recommended age for screening in Brazil. Diagnosis was predominantly performed by clinical examination, with delays in obtaining the histological diagnosis, and the stage at diagnosis was high, and these facts were associated with the health system limitations. KEYWORDS: breast neoplasm; age groups; cancer screening.

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Câncer de Mama em Mulheres Jovens: Análise de 12.689 Casos

Cited by 20 publications

References 15 publications

Tumor biological profile of patients up to 50 years of age in a countryside city of São Paulo

Tumor biological profile of patients up to 50 years of age in a countryside city of São Paulo

Análise de Prescrições Médicas de Pacientes Oncológicos / Analysis of Medical Prescriptions of Cancer Patients

Evaluation of clinical, pathological and epidemiological profile of patients with breast cancer in the microregion of Lavras – MG

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