Cancers de la thyroïde

Leenhardt, Laurence; Ménégaux, Fabrice; Franc, B.; Hoang, Catherine; Salem, Sarra Fekih; Bernier, Marie‐Odile; Dupasquier-Fédiaevsky, L.; Marois, Edith; Rouxel, A.; Chigot, J.-P.; Chérié-Challine, L.; Aurengo, André

doi:10.1016/j.emcend.2004.10.003

Cited by 21 publications

(15 citation statements)

References 101 publications

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“…Only the ionizing radiations received during childhood have an established responsibility for the occurrence of thyroid cancer. The thyroid cancers of Ukrainian and Belarusian children secondarily to the Chernobyl accident are a dramatic illustration of this [5].…”

Section: Introductionmentioning

confidence: 99%

“…The prognostic factors of thyroid cancers are well known and allow correctly predicting the long term fate of the patients. There are the prognostic factors related to the characteristics of the patients like the sex or the age, those related to the initial tumor such as size and histological type and those related to the initial treatment [5].…”

Section: Introductionmentioning

confidence: 99%

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Thyroid Cancer in Western Algeria: Histopathological and Epidemiological Study

Benouis¹,

Bekkouche²,

Merad³

et al. 2017

JCT

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Thyroid cancer is relatively rare, about 1% of all cancers combined. However, it accounts for 88% of all cancers of the endocrine organs. In recent years, the incidence of thyroid cancer has increased considerably compared to other types of endocrine cancers. The aim of our work is to study the epidemiological profile of thyroid cancer in the western part of Algeria and to determine the influence of sex, age and histological type. Patients and methods: Our study focuses on 1376 cases of thyroid cancer in patients attending the nuclear medicine department at the university hospital of Tlemcen over a period of 3 years, from 2013 to 2015. The average age of patients is estimated at 43. Each patient underwent an anatomo-histopathological examination of the surgical specimen. The data entry is done through the SPSS 20 statistical software. Results: The rates of the thyroid cancers listed during the three years of studies (2013-2014-2015) are 32.12%, 34.44% and 33.43% respectively. Our study shows that the female sex is largely incriminated (94.75%) compared to the male sex. The age group mostly affected was that ranging from 40 to 60 with 45.88%. The anatomo-histopathological analysis revealed that the papillary carcinoma is the most frequent histological type with 85.47% followed by the vesicular carcinoma with 14%, the medullary cancer MTC with 0.43%, and finally the anaplastic carcinoma with 0.07%. Conclusion: the epidemiological surveillance contributes to a better knowledge of thyroid carcinoma allowing a good patient management in Algeria. Early detection of small size cancers and the use of high-performing technologies will result in a decrease of the mortality rate associated to this type of cancer.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Thyroid Cancer in Western Algeria: Histopathological and Epidemiological Study

Benouis¹,

Bekkouche²,

Merad³

et al. 2017

JCT

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“…L'incidence rapportée dans les différentes séries avoisine les 4 % [2,3]. Les métastases siègent essentiellement au niveau des poumons (40 à 80 %) ; moins fréquemment au niveau du squelette (2,5 à 12,5 %) [4], atteignant par ordre de fréquence décroissante : le rachis, le bassin, la ceinture scapulaire, le crâne et le sternum. D'autres localisations métastatiques sont rapportées notamment au niveau du cerveau qui représente la 3 ème localisation métastatique.…”

Section: Commentairesunclassified

“…En immunohistochimie, le diagnostic de malignité est fait devant : la perte d'immunoréactivité de la thyroïde peroxydase [TPO], l'expression de la galectine 3, de l'HBME-1, de ret, de CK19 et de peroxisome proliferator activated receptor (PPAR) gamma. Celui d'agressivité tumorale est fait devant l'un des signes suivants : augmentation de l'indice de prolifération, perte d'expression de bcl2, expression de p53 [4]. Concernant les métastases, leur analyse histologique peut être difficile d'où l'intérêt des marquages immunohistochimiques.…”

Section: Histologieunclassified

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