Candida‐associated denture stomatitis. Aetiology and management: A review: Part1. Factors influencing distribution of candida species in the oral cavity

Webb, B. C.; Thomas, Catherine; Willcox, Mark; Harty, D. W. S.; Knox, K. W.

doi:10.1111/j.1834-7819.1998.tb00152.x

Cited by 205 publications

(208 citation statements)

References 52 publications

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“…In fact, a pH equal to 3 is optimal not only for the adhesion of the yeasts, but also for the enzymatic activity of the proteinases that, together with the lipases, are the most important factors of virulence of Candida because of their cytotoxic and cytolytic effects. Moreover, high levels of carbohydrates present in the saliva can act as an additional nourishing source for the Candida yeasts, that, by metabolizing these sugars, produce acid metabolic products and contribute to maintain low the environmental pH (1).…”

Section: The Salivamentioning

confidence: 99%

“…Its primary location is the posterior tongue and other oral sites as the mucosa, while the film that covers the dental surfaces is colonized secondarily (1). Frequently, when the host defense system suffers because of any alterations, like immunodeficiency, C. albicans become virulent and generates candidiasis, that can be manifested through various clinical forms, involving one or more oral sites, up to affect the whole oral cavity and to disseminate into invasive forms.…”

Section: Introductionmentioning

confidence: 99%

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Candida-associated denture stomatitis

Salerno

Pascale²,

Contaldo³

et al. 2011

Med Oral

288

231

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Candida albicans is a dimorphic yeast strongly gram positive able to live as normal commensal organism in the oral cavity of healthy people. It is the yeast more frequently isolated in the oral cavity. Under local and systemic factors related to the host conditions, it becomes virulent and responsible of oral diseases known as oral candidiasis. It has been shown that the presence of denture is a predisposing factor to the onset of pathologies related to C. albicans. Clinical studies have shown that C. albicans is not only able to adhere to the mucous surfaces, but also to stick to the acrylic resins of the dental prostheses. Both the plaque accumulated on the denture and the poor oral hygiene contribute to the virulence of Candida, offering the clinical picture of Candida-associated denture stomatitis. The therapeutic strategies currently adopted in the clinical practice to overcome these fungal infections provide for the use of topical and/or systemic antifungal and topical antiseptics and disinfectants, the irradiation with microwaves and the accurate mechanical removal of the bacterial plaque from the denture surfaces and from the underlying mucosa. A correct oral hygiene is important for the control of the bacterial biofilm present on the denture and on the oral mucosa and it is the fundamental base for the prophylaxis and the therapy of the Candidaassociated denture stomatitis.

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Section: The Salivamentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Candida-associated denture stomatitis

Salerno

Pascale²,

Contaldo³

et al. 2011

Med Oral

288

231

View full text Add to dashboard Cite

show abstract

“…A similar situation occurs in patients with Sjo Ègren's syndrome [22]. Furthermore, the wearing of dentures can lead to a candida-associated denture stomatitis, a condition caused by a disruption of the oral micro¯ora due to the presence of a biomaterials prosthesis [23].…”

Section: Discussionmentioning

confidence: 96%

Effect of probiotic bacteria on prevalence of yeasts in oropharyngeal biofilms on silicone rubber voice prostheses in vitro

Mei¹,

Free

Elving³

et al. 2000

Journal of Medical Microbiology

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The proliferation of yeasts in the mixed bacterial and fungal bio®lms colonising silicone rubber voice prostheses in laryngectomised patients is the main cause of malfunctioning of the valve mechanism on the oesophageal side of the prostheses. Indwelling voice prostheses usually have to be replaced every 3±4 months. The consumption of probiotic bacteria is largely motivated by health claims related to the urogenital and lower digestive tract, but not to the upper digestive tract. The present study examined the in¯uence of probiotic bacteria on the prevalence of yeasts in oropharyngeal bio®lms on silicone rubber voice prostheses, as formed in a modi®ed Robbins device. Exposure of oropharyngeal bio®lms on voice prostheses to suspensions of Bi®dobacterium infantis 420 or Enterococcus faecium 603 did not signi®cantly reduce the number of yeasts in the bio®lm. However, suspensions of Lactobacillus fermentum B54, L. rhamnosus 744 or L. lactis cremoris SK11 led to a reduction in the number of yeasts harvested from the voice prostheses. Suspensions of L. casei Shirota and Streptococcus thermophilus B signi®cantly reduced the number of yeasts in the bio®lm to 39% and 33%, respectively. The reduction brought about in yeast prevalence in the mixed bio®lm was greatest by exposure to a suspension of L. lactis 53, with yeast prevalence only 4% of the control. In conclusion, the study demonstrated that the prevalence of yeasts in oropharyngeal bio®lms on silicone rubber voice prostheses might be controlled by consumption of probiotic bacteria.

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“…However, NaOCl was used in a low concentration (0.5%), which seems to present no detrimental effect on resilient denture liners. 15,16 This result is important since this concentration may result in adequate control of biofilm formation without alteration the original characteristics of the denture liners. However, it is worth saying that in this study, the effects on the assessed properties of resilient liners were tested only for 14 days and this may have influenced the results, especially considering that other liners may be used for longer periods.…”

Section: Discussionmentioning

confidence: 99%