Candidate Medicinal Plant Species of Djiboutian Pharmacopeia for Testing Pharmacological Activities on Common Microbial Diseases

Abstract

Objective: The aim of the study was to conduct an ethnobotanical study focused on the medicinal plants used in Randa (Djibouti) for testing pharmacological activities on common microbial diseases.Methods: Plant Ratio (PR), Index of Performance (IP) and the high Informant Consensus Factors (ICF) were calculated to select candidate medicinal species with a pharmacological potential. Results:From this previous work, it was found that the high Informant Consensus Factors, ICF (0.82) for the category of microbial diseases turned out to merit further perusal. The findings particularly gave an imminent insight that stimulated additional investigations and analyses. Different factors, including Plant Ratio (PR) and Index of Performance (IP) were employed for comparison leading to the selection of 18 candidates species, for subsequent pharmacological screening, and testing for antimicrobial activities. Comparison of the information with that accessed from the literature implicitly hinted that the Djiboutian traditional medical system shares much in common with other traditional medical systems. At least six out of the 18 species have not been pharmacologically tested before. Conclusion:The comparison of differents factors (IP2, PR and FL') of plants screening have showed that 18 plants species of Randa region, have good healing potential for infectious diseases. This may inspire continued research to build a comprehensive ethnobotanical and ethnopharmacological profiles of the species anticipated to be of the most promising potential for Djibouti and beyond.

A Review on the Main Phytoconstituents, Traditional Uses, Inventions, and Patent Literature of Gum Arabic Emphasizing Acacia seyal

“…Several studies conducted in recent decades revealed that extracts from the bark of A. seyal have antibacterial action [25,38,39], antimalarial effect [40], antimycobacterial effect, cyclooxygenase inhibition effect [41], molluscicidal activity [42], and anticancer activities [43,44]. Acacia gum has been established to possess several therapeutic actions, such as hypoglycemic, antidiabetic, antioxidant, immunomodulatory, and cytoprotective antiulcer, and has prebiotic properties [18,25].…”

Bridelia Scandens Wild. A New Source for Podophyllotoxin Production in Vitro by Feeding Coniferyl Alcohol

“…Many clinically useful prescription drugs have originated from traditional medicinal plants. Since there are many traditional medicinal plants widely used by society, it is worth subjecting these plants to investigate for the discovery of drugs with anticipation of obtaining new bioactive substances [1].…”

“…The method allows the growth of plant materials that otherwise would be difficult to grow in nature because of geographic, climatic, or seasonal restrictions. From the plant materials, the production of secondary metabolites can also be manipulated in vitro, which can lead to overproduction of compounds of interest, or the production of chemicals not originally found in native plants [1].…”