Canine angiostrongylosis: an emerging disease in Europe

Helm, Jenny; Morgan, Eric R.; Jackson, Mark W.; Wotton, P. R.; Bell, R.

doi:10.1111/j.1476-4431.2009.00494.x

Cited by 103 publications

(160 citation statements)

References 79 publications

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“…In dog, distinct isolated endemic foci were reported during the last century in south-western France, Ireland, Switzerland, Southeast England and Wales, and Denmark. Canine angiostrongylosis is clearly emerging both in North America [6] and Europe [7] where it was recently further recorded in Greece [8], The Netherlands [9], different parts of Germany [10], Italy [11], Slovakia [12] Poland [13] and Hungary [14]. In temperate Western Europe climatic conditions are highly suitable to the completion of Angiostrongylus vasorum life cycle and Belgium is part of a vast area characterized by its high predicted suitability for parasite transmission [15].…”

Section: Introductionmentioning

confidence: 99%

First report of a fatal autochthonous canine Angiostrongylus vasorum infection in Belgium

Jolly

Poncelet²,

Lempereur

et al. 2015

Parasitology International

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Canine angiostrongylosis is considered as an emergent disease in Europe and Canada. A fatal case of Angiostrongylus vasorum infection is described in a four and a half month old puppy born in Belgium. The dog was presented with marked neurological disorders, body weight loss, a profound weakness and mild respiratory signs. The dog was given antibiotics and mucolytic compounds with very little improvement and consequently was referred to a specialist for additional examinations. As the general condition of the dog was rapidly declining, the animal was euthanized shortly after on its owners' request and a necropsy was carried out. Extensive gross pulmonary lesions were observed and histopathological examination revealed the presence of numerous larvae with morphology compatible with A. vasorum. Larvae were also found in the product of a bronchoalveolar lavage but fecal material was not examined. The presence of A. vasorum circulating serum antigen was demonstrated through ELISA; additionally an A. vasorum specific PCR was performed on brain material and yielded a positive result. This case confirms that the clinical diagnosis of canine angiostrongylosis can be very challenging especially when respiratory signs are absent or very mild such in the present case. This is the first reported case of canine angiostrongylosis in Belgium.

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Section: Introductionmentioning

confidence: 99%

First report of a fatal autochthonous canine Angiostrongylus vasorum infection in Belgium

Jolly

Poncelet²,

Lempereur

et al. 2015

Parasitology International

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“…A moderate northward expansion of the predicted range is seen when running the model with a 2 °C global temperature increase ). Nevertheless, other factors in the distribution and expansion of the parasite also need to be considered, such as the growing fox population and transportation of dogs Helm et al 2010;Elsheikha et al 2014). Although the raccoon dog has a wide range of parasites and a similar helminth spectrum to those of the red fox, A. vasorum has not been diagnosed in a raccoon dog so far (Thiess et al 2001;Sutor et al 2011;Bruzinskaite-Schmidhalter et al 2012;Sutor et al 2014).…”

Section: Discussionmentioning

confidence: 99%

“…Symptoms of angiostrongylosis range from subclinical to severe and A. vasorum infection may have a fatal outcome (Simpson and Neal 1982;Chapman et al 2004;. In dogs, disease is characterised by coughing and dyspnoea, exercise intolerance and weight loss; neurological and gastrointestinal signs and haemorrhagic diathesis are further symptoms that may occur (Chapman et al 2004;Koch and Willesen 2009;Helm et al 2010). …”

Section: Introductionmentioning

confidence: 99%

“…A test for the serological detection of circulating antigen (Angio Detect TM Test, IDEXX Laboratories, Westbrook, Maine, USA) for rapid diagnosis is now also commercially available for use in veterinary clinics (Schnyder et al 2014). Angiostrongylosis in dogs is considered an emerging disease in Europe (Morgan et al 2005;Koch and Willesen 2009;Helm et al 2010). Studies from Germany indicate an increasing risk of infection for German dogs in recent years Barutzki and Schaper 2009;Taubert et al 2009;Barutzki and Schaper 2011;Barutzki 2013).…”

Section: Introductionmentioning

confidence: 99%

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Detection of Angiostrongylus vasorum in Red Foxes (Vulpes vulpes) from Brandenburg, Germany

Härtwig¹,

Schulze²,

Barutzki

et al. 2015

Parasitol Res

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Angiostrongylus (A.) vasorum is a nematode that causes angiostrongylosis in domestic and wild canids. Red foxes (Vulpes vulpes) and raccoon dogs (Nyctereutes procyonoides) are suspected of providing a wildlife reservoir for A. vasorum infections in pet dogs. To obtain data on the occurrence of A. vasorum in wildlife, red fox and raccoon dog carcasses (hunted or found dead) were collected from January to September 2009 in the Federal State of Brandenburg, Germany. Lung tissue samples were subjected to DNA extraction and examined for the presence of A. vasorum DNA by means of real-time PCR. A. vasorum DNA was detected in 11 out of 122 (9.0 %) lungs of red foxes and in none of the lung samples of raccoon dogs. These data suggest that red foxes are a reservoir of A. vasorum infections for pet dogs in this area.

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“…Snails and slugs become infected by foraging on the faecal deposits and thereby serve as intermediate hosts (Bolt et al 1993). Over the past decade, the prevalence of A. vasorum in wildlife has increased in several European countries (Morgan et al 2005;Van Doorn et al 2009;Helm et al 2010), the most important definitive hosts being domestic dogs and foxes (Koch and Willesen 2009), whilst the modes of transmission to the final host are still unclear (Morgan et al 2005).…”

Section: Introductionmentioning

confidence: 99%

PCR detection of Angiostrongylus vasorum in faecal samples of dogs and foxes

et al. 2010

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The cardiovascular nematode Angiostrongylus vasorum is spreading in the fox and dog populations of northern Europe. A. vasorum can result in severe clinical manifestations in dogs; therefore, specific diagnosis is crucial for assessing its prevalence. In the present study, faecal samples from foxes and domestic dogs were tested by a new polymerase chain reaction (PCR) targeting the second internal transcribed region of the ribosomal DNA (ITS2) of A. vasorum. Initial isolation of faecal larvae by sieving facilitated the processing of larger sample volumes and allowed for the recovery of dead larvae from frozen samples. The sieve-PCR method enabled the identification of a single larva per 2 g of faecal sample and did not amplify DNA of a range of canine helminths, thus presenting a non-invasive tool for wildlife surveillance and for confirmative diagnosis in dogs. Abstract The cardiovascular nematode Angiostrongylus vasorum is spreading in the fox and dog populations of northern Europe. A. vasorum can result in severe clinical manifestations in dogs; therefore, specific diagnosis is crucial for assessing its prevalence. In the present study, faecal samples from foxes and domestic dogs were tested by a new polymerase chain reaction (PCR) targeting the second internal transcribed region of the ribosomal DNA (ITS2) of A. vasorum. Initial isolation of faecal larvae by sieving facilitated the processing of larger sample volumes and allowed for the recovery of dead larvae from frozen samples. The sieve-PCR method enabled the identification of a single larva per 2 g of faecal sample and did not amplify DNA of a range of canine helminths, thus presenting a non-invasive tool for wildlife surveillance and for confirmative diagnosis in dogs.

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Canine angiostrongylosis: an emerging disease in Europe

Abstract: The prognosis appears to be very dependent upon the severity of clinical signs at presentation. A. vasorum can be fatal and death may be sudden. However, if a prompt diagnosis is made and appropriate treatment is administered complete clinical resolution is possible.

Cited by 103 publications

References 79 publications

First report of a fatal autochthonous canine Angiostrongylus vasorum infection in Belgium

First report of a fatal autochthonous canine Angiostrongylus vasorum infection in Belgium

Detection of Angiostrongylus vasorum in Red Foxes (Vulpes vulpes) from Brandenburg, Germany

PCR detection of Angiostrongylus vasorum in faecal samples of dogs and foxes

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