Canine Choroid Plexus Tumor with Intracranial Dissemination Presenting as Multiple Cystic Lesions

Oura, Trisha J.; Early, Peter J; Jennings, Sydney; Lewis, Melissa J.; Tobias, Jeremy R.; Thrall, Donald E.

doi:10.1155/2013/759054

Cited by 11 publications

(19 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It has been reported in dogs with mammary carcinoma (Pumarola and Balasch 1996, Mandara and others 2007, Behling-Kelly and others 2010), intestinal carcinoma (Stampley and others 1987), cutaneous squamous cell carcinoma (Salvadori and others 2004) and a choroid plexus carcinoma (Patnaik and others 1980, Lipsitz and others 1999, Oura and others 2010). Haematogenous spread is the most frequently reported mechanism of metastasis to leptomeninges (Kesari and Batchelor 2003, DeAngelis and Boutros 2005).…”

Section: Discussionmentioning

confidence: 95%

Histiocytic sarcoma in a flat‐coated retriever with central and peripheral nervous system sarcomatosis

Marcinowska¹,

Constantino‐Casas²,

Dobson³

2014

Vet Record Case Reports

View full text Add to dashboard Cite

A six-year-old male, neutered, flat-coated retriever presented with a suspicion of localised histiocytic sarcoma (HS) in the right axillary region, fine needle aspirate was suggestive of HS. The dog was prescribed four doses of radiotherapy (4×850 cGy). At the first treatment tru-cut biopsies of the mass were taken, and histopathology was consistent with the cytological diagnosis. At the third treatment, the dog developed five cutaneous nodules, and microscopy confirmed HS. Seven weeks after radiotherapy, the patient presented with severe progressive hind limb ataxia and a flaccid tail. Due to the severity of clinical signs, euthanasia was performed. Postmortem examination revealed neoplastic cells within the right axillary mass, liver, kidney, adrenal gland and diffusely infiltrating the brain, lumbar spinal cord, cauda equina and spinal nerves, consistent with metastatic HS. This case is unusual in the diffuse and infiltrative dissemination of the tumour throughout the CNS and nerve roots.

show abstract

Section: Discussionmentioning

confidence: 95%

Histiocytic sarcoma in a flat‐coated retriever with central and peripheral nervous system sarcomatosis

Marcinowska¹,

Constantino‐Casas²,

Dobson³

2014

Vet Record Case Reports

View full text Add to dashboard Cite

show abstract

“…The most common sites of intracranial cysts in animals include the fourth ventricle and cerebellopontine angle (2, 6, 8, 10, 12, 14–16) and the area above the quadrigeminal plate (4–7, 9). There are individual reports of cysts located in the brainstem (6, 9, 11, 13); cerebellum (3); and frontal (11), diencephalic (1), and hypophyseal (31) regions. Lesions involving the cerebellar, medullary, and fourth ventricular regions can be best approached from the caudal direction (suboccipital approach, e.g., cystoperitoneal shunting).…”

Section: Discussionmentioning

confidence: 99%

“…Choroid plexus tumors account for 10% of all intracranial tumors in dogs, with the lateral, third, and fourth ventricles being the commonly involved sites (1). Based on this study the most affected breed is the Golden Retriever, and female predominance has been noted.…”

Section: Introductionmentioning

confidence: 99%

A Recurrent Suprapituitary Ependymal Cyst Managed by Endoscopy-Assisted Transsphenoidal Surgery in a Canine: A Case Report

Lehner

Garamvölgyi

Jakab³

et al. 2019

Front. Vet. Sci.

View full text Add to dashboard Cite

A 9-years-old spayed female mixed-breed dog was referred for the evaluation of intermittent head tremors, obtundation, long-standing blindness, and a tendency to seek confined spaces. The dog lost its vision 6 months before the current presentation. A menace response was absent on ophthalmological examination. Neurological examination did not show any abnormalities. A cyst measuring 16 × 18 × 14 mm was observed above the pituitary gland on magnetic resonance imaging. It extended toward the frontal area and compressed the optic chiasm and hypothalamic regions. A minimum preoperative database, including the findings of other required blood tests, was prepared. No abnormal laboratory findings were observed. Endoscopy-assisted transsphenoidal hypophysectomy was performed to remove the pituitary gland, drain the cyst, and partially excise the cyst wall. Normal pituitary gland tissue was observed on histopathology, and the mass was found to have a neuroendocrine or ependymal origin on cytology. Strict post-operative laboratory tests were performed at 1-h intervals for 24 h. An empty sella turcica region, and a collapsed and empty cyst wall was observed on follow-up magnetic resonance imaging. After 3 days of observation, the dog was discharged with a prescription of substitution therapy. However, the dog presented with the same signs and symptoms 73 days after the surgery. Cyst recurrence was apparent on magnetic resonance imaging. The owner requested euthanasia, and an ependymal cyst was observed on necropsy. To the best of our knowledge, we present the first case of an intra- and suprasellar ependymal cyst, and its surgical management in a canine. The findings from this case suggest that endoscopic transsphenoidal drainage and hypophysectomy could be a good surgical approach in cases where involvement of the pituitary gland is confirmed or strongly suspected on the basis of cytological and imaging findings.

show abstract

“…Some tend to expand causing symptoms of obstruction at the lateral apertures (Brewer et al 2010;Galano et al 2002). Moreover, cystic lesions inside the fourth ventricle are an unusual manifestation of choroid plexus tumors in dogs (Oura et al 2013).…”

Section: Obstruction Of the Lateral Aperturesmentioning

confidence: 99%

Hydrocephalus in Animals

Schmidt

Ondreka

2019

Pediatric Hydrocephalus

View full text Add to dashboard Cite

Canine Choroid Plexus Tumor with Intracranial Dissemination Presenting as Multiple Cystic Lesions

Cited by 11 publications

References 9 publications

Histiocytic sarcoma in a flat‐coated retriever with central and peripheral nervous system sarcomatosis

Histiocytic sarcoma in a flat‐coated retriever with central and peripheral nervous system sarcomatosis

A Recurrent Suprapituitary Ependymal Cyst Managed by Endoscopy-Assisted Transsphenoidal Surgery in a Canine: A Case Report

Hydrocephalus in Animals

Contact Info

Product

Resources

About