2020
DOI: 10.14202/vetworld.2020.68-72
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Canine demodicosis: Hematological and biochemical alterations

Abstract: Background and Aim: One of the most common cutaneous infections seen in veterinary canine practice is canine demodicosis. Demodicosis is a parasitic skin infection with a possible impact on acute-phase proteins (APPs) and oxidant-antioxidant balance. This study aimed to estimate the possible alterations in hematological, biochemical, oxidant-antioxidant, and APP (C-reactive protein [CRP] and albumin) profiles in naturally infected dogs with demodicosis. Materials and Methods: This study enrolled 21 do… Show more

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Cited by 21 publications
(18 citation statements)
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“…Abundance in ROS overwhelms the antioxidant system, and the eye tissue became overloaded with ROS ( 60 ). The increase in MDA level could be attributed to increasing ROS output or as compensation for the reduction in antioxidants ( 24 ). Alterations in the hydration of the cornea are factored in resultant oxidative stress ( 61 ).…”
Section: Discussionmentioning
confidence: 99%
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“…Abundance in ROS overwhelms the antioxidant system, and the eye tissue became overloaded with ROS ( 60 ). The increase in MDA level could be attributed to increasing ROS output or as compensation for the reduction in antioxidants ( 24 ). Alterations in the hydration of the cornea are factored in resultant oxidative stress ( 61 ).…”
Section: Discussionmentioning
confidence: 99%
“…Oxidative stress was described in numerous diseases in pet animal practice; both infectious and non-infectious etiologies were associated with damaging effects of oxidative stress mechanisms ( 24 ).…”
Section: Introductionmentioning
confidence: 99%
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“…A significant mobilization of NEFA in dairy cows associated with increase in free oxygen radicals (e.g., ROS) production [ 36 ]. Increased free-radical production could be associated with the increase in MDA levels [ 37 ].…”
Section: Discussionmentioning
confidence: 99%
“…Researchers found found significant changes in morphological and biochemical parameters of the blood in the generalized form of demodicosis in dogs, which indicate functional disorders in the liver and kidneys. Meanwhile, 2.5 months after treatment, morphological and biochemical parameters of the blood probably stabilized and acquired physiological parameters [17,18].…”
Section: Discussionmentioning
confidence: 99%