2023
DOI: 10.4018/978-1-6684-5652-1.ch006
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Cannabinoid Neurobiology and Medical Cannabis Intervention for Amyotrophic Lateral Sclerosis (ALS)

Abstract: Amyotrophic lateral sclerosis (ALS), a neurodegenerative condition that leads to muscle wasting, weakness, and stiffness, is characterized by progressive loss of upper and lower extremity muscle cells. The development of therapies that do more than just slow disease progression is essential. Cannabinoids with a broad-spectrum neuroprotection profile appear to have the potential to manage ALS. Cannabinoids can reduce excitotoxicity and neuroinflammation via activating CB1 and CB2 receptors. To increase treatmen… Show more

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