Capillary electrochromatographic separation of amino acid enantiomers with molecularly imprinted polymers as chiral recognition agents

Chiral separation by chromatographic and electromigration techniques. A Review

“…Lin et al [541] applied a thermally induced in situ polymerization procedure for the preparation of an imprinted polymer using d-phenylalanine as a print molecule. This phase showed high chiral recognition ability for phenylalanine, but was weak for tyrosine and phenylglycine.…”

Molecularly imprinted monolithic stationary phases for liquid chromatographic separation of enantiomers and diastereomers

“…sequently, the same approach was applied to prepare the molecularly imprinted stationary phases for the 2 .2. Preparation of molecularly imprinted separation of racemic mixtures in CEC [17][18][19][20].…”

Short columns with molecularly imprinted monolithic stationary phases for rapid separation of diastereomers and enantiomers

“…This type of MIPs exhibited recognition ability for some imprint molecules such as theophylline, nicotine, diaminonaphthalene, cinchona alkaloid and enantiomers of phenylalanine anilide [13][14][15][16][17]. Subsequently, Schweitz et al [18][19][20][21]23] and Lin et al [22] used the same approach for the preparation of molecularly imprinted stationary phases for the separation of racemic mixtures in CEC. Using this technique, MIPs can be synthesized directly inside stainless steel columns or capillary columns without the tedious procedures of grinding, sieving and column packing.…”