Capillary electrophoresis becoming an effective tool for explaining inconsistent results of interactions between nonionic polymers and phosphate surfactants

Study of molecular interactions by nonequilibrium capillary electrophoresis of equilibrium mixtures: Originations, developments, and applications

“…CE is a general term for a class of liquid‐phase separation methods and techniques implemented by taking the capillary as the separation channel and a high‐voltage electric field as the driving force, based on the characteristics of the sample charge, size, isoelectric point, polarity, affinity behavior, and phase distribution. CE has several advantages, including high separation efficiency, short analysis time, low sample and reagent consumption (nanoliter injection volumes, picograms of proteins) [20], a wide range of analytes (such as inorganic ions [21], small organic molecules [22], proteins [23], polymers [24], and whole viruses or cells [25]), and direct analysis of complex matrix samples. Furthermore, CE takes a physiological saline buffer solution as its separation medium; thus, molecules, such as enzymes, receptors, and DNA, are not easily denatured, making this a suitable method for the separation and analysis of biologically active macromolecules.…”

A dual preconcentration method by combining micro matrix solid‐phase dispersion extraction with field‐enhanced sample injection and micelle to cyclodextrin stacking for sensitive analysis of neutral coumarins

“…CE is a useful analytical tool to separate chemical mixture based on different electrophoretic mobilities. It has gained tremendous attention and became an indispensible tool for the analysis of complicated matrix samples such as biologics, due to its advantages of simple operation, high separation efficiency, small consumption of sample and organic reagent, and various separation modes [11,12]. However, low detection sensitivity, which due to the small injection volume and the short detection optical path, hides its wide applications [13].…”