Capnocytophaga sputigena pneumonia and bacteremia in a patient with diabetes and gastric cancer

Capnocytophaga sputigena bloodstream infection in hematopoietic stem cell transplantations: two cases report and review of the literature

“…using different methods have shown that clindamycin, linezolid, tetracycline, chloramphenicol, imipenem and β-lactamase inhibitor combinations displayed in vitro activities against this bacterium. In contrast, most strains are reported as resistant to polymyxin, fusidic acid, fosfomycin and trimethoprim 13 . A recent study, however, demonstrated that a high proportion of Capnocytophaga sputigena isolates were β-lactamase-positive and that β-lactam-resistant isolates, resistant to amoxacillin, amoxacillin plus clavulanic acid and third generation cephalosporins, harboured the β-lactamase genes bla CfxA or bla CSP-1 14 .…”

“…This is a limitation of our report as the species identification is key to implementinfection control measures and patients care as the species can hypothesize the source of infection such as the animal contact 10 . Since there is no Clinical & Laboratory Standards Institute (CLSI) nor European Committee on Antimicrobial Susceptibility Testing (EUCAST) recommendation for susceptibility break points for this genus; the spectrum of antibiotics and the duration of treatment is based on clinical reports 13 . Antimicrobial susceptibility of Capnocytophaga spp.…”

“…Since there is no Clinical & Laboratory Standards Institute (CLSI) nor European Committee on Antimicrobial Susceptibility Testing (EUCAST) recommendation for susceptibility break points for this genus; the spectrum of antibiotics and the duration of treatment is based on clinical reports 13 . Antimicrobial susceptibility of Capnocytophaga spp.…”

Capnocytophaga sputigena: An unusual cause of community-acquired pneumonia

“…Infection can occur in immunocompetent hosts, and Lo et al reported the case of a bilateral pneumonia with pleural effusion in an 84-year-old man. C. sputigena was detected on blood cultures [3]. Li et al presented a case of a 68-year-old immunocompetent man with persistent pleural effusion for whom C. sputigena was detected on a pleural drain [4].…”

“…Moreover, clinical response was correlated with antibiotic susceptibility as the introduction of a beta-lactamase inhibitor improved the clinical course. The bacterium was identified by MALDI-TOF mass spectrometry, which is the technique that has been used in recent case reports [[3], [4], [5]].…”