Capsular bag opacification with a new accommodating intraocular lens

Abstract

The study IOL maintained an expanded capsular bag secondary to the large size of the haptic elements, which appears to prevent capsular bag opacification.

Evaluation of stability and capsular bag opacification with a foldable intraocular lens coupled with a protective membrane in the rabbit model

“…Expansion of the capsular bag with associated prevention of postoperative capsule opacification has also been described in association with different IOLs. These include the Spring-loaded IOL by Hara et al, 22,23 the Concept 360 IOL (Corneal Laboratoire), 24 the Synchrony IOL (Abbott Medical Optics, Inc.), [25][26][27][28][29] the Fluidvision IOL (Powervision, Inc.), 9,10 and a disk-shaped single-piece hydrophilic acrylic IOL suspended between 2 haptic rings connected by a pillar of haptic material (Anew Optics, Inc.). 7,8 The retention of postoperative capsular bag clarity by these devices likely occurs secondary to the complex interactions of many factors.…”

“…The rabbit model was chosen for its accelerated development of posterior capsule opacification (PCO), in which 1 month of implant time is approximately equivalent to 1 to 2 years in humans for PCO development. [7][8][9][10] Anesthesia, surgical preparation, and bilateral phacoemulsification with IOL implantation were performed according to protocol described in previous studies. [7][8][9][10] Briefly, a fornix-based conjunctival flap was fashioned.…”

“…The extent and severity of anterior capsule opacification (ACO) and PCO were scored according to previously described methods. [7][8][9][10] After gross examination and photography, all globes were sectioned and the anterior segments, including the capsular bags, were processed for standard light microscopy and stained with hematoxylin-eosin (H&E).…”

Biomimetic Accommodating Intraocular Lens Using a Valved Deformable Liquid Balloon

“…These include the possible development of capsular fibrosis and opacification. There is evidence in the literature that devices that fill out the capsular bag have low rates of opacification (30)(31)(32). However, further work needs to be done in order to evaluate this particular design.…”

Biological performance of functionalized biomedical polymers for potential applications as intraocular lens

“…16 The eye turbidity of the anterior or posterior capsule is associated with the fibrosis, migration, and proliferation of HLEpiC. So the adhesion, proliferation, and morphology of the cells can provide a basis for evaluating the compatibility of the IOL capsules.…”