The physicochemical characterization of water of the Mbe Plateau was carried out starting from thirty-two (32) samples of water taken between November 2017 and May 2018 in six months (rain season with a seasonal intercalation enters mid-January and at the end of February known as small dry season). Four (04) boreholes (Massa, Dieu le veut, Ingha and Ivoumba), three (03) rivers (Maty, Mary and Gamboma) and one (01) well (Ignié) were sampled during this study. The study of this water was based on measured parameters in-situ (the temperature, TDS, pH, the EC, dissolved oxygen, dissolved complete iron and salinity) and at the laboratory in particular: hardness, Ca