Características clínicas de la pancreatitis aguda en México

González-González, J.A.; Castañeda-Sepúlveda, Rafael; Martínez-Vazquez, Manuel; García-Compeán, Diego; Flores-Rendón, Ángel Ricardo; Garza, Héctor J. Maldonado; Bosques-Padilla, Francisco; Garza-Galindo, Aldo Azael

doi:10.1016/j.rgmx.2012.08.002

Cited by 14 publications

(9 citation statements)

References 36 publications

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“…Each item was marked: green-1: low risk; red-0: high risk and yellow-0: unclear risk of bias. A total of 9 points was the maximum that could be assigned (Table 2) (Milheiro et al, 1995; Yeung et al, 1996; Abou-Assi et al, 2002; Gürleyik et al, 2005; Muller et al, 2006; De Waele et al, 2007; Knoepfli et al, 2007; Uomo et al, 2007; Wu et al, 2008; Radenkovic et al, 2009; Lautz et al, 2011; Gompertz et al, 2012, 2013; Gonzalez-Gonzalez et al, 2012; Gomez Beltran et al, 2013; Gornik et al, 2013; Nijmeijer et al, 2013; Spanier et al, 2013; Albulushi et al, 2014; de-Madaria et al, 2014; Pant et al, 2014; Zuidema et al, 2014; Ho et al, 2015; Ocampo et al, 2015; Wang et al, 2015; Yue et al, 2015; Dombernowsky et al, 2016; Karpavicius et al, 2016; Mole et al, 2016; Parniczky et al, 2016; Rashidi and Røkke, 2016; Weitz et al, 2016; Zhang et al, 2016).…”

Section: Resultsmentioning

confidence: 99%

Aging and Comorbidities in Acute Pancreatitis I: A Meta-Analysis and Systematic Review Based on 194,702 Patients

et al. 2019

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Background: Acute pancreatitis (AP) is one of the most common cause of hospitalization among gastrointestinal diseases worldwide. Although most of the cases are mild, approximately 10–20% of patients develop a severe course of disease with higher mortality rate. Scoring systems consider age as a risk factor of mortality and severity (BISAP; >60 years, JPN>70 years, RANSON; >55 years, APACHE II >45 years). If there is a correlation between aging and the clinical features of AP, how does age influence mortality and severity? Aim: This study aimed to systematically review the effects of aging on AP. Methods: A comprehensive systematic literature search was conducted in the Embase, Cochrane, and Pubmed databases. A meta-analysis was performed using the preferred reporting items for systematic review and meta-analysis statement (PRISMA). A total of 1,100 articles were found. After removing duplicates and articles containing insufficient or irrelevant data, 33 publications involving 194,702 AP patients were analyzed. Seven age categories were determined and several mathematical models, including conventional mathematical methods (linear regression), meta-analyses (random effect model and heterogeneity tests), meta-regression, funnel plot and Egger's test for publication bias were performed. Quality assessment was conducted using the modified Newcastle–Ottawa scale. The meta-analysis was registered in the PROSPERO database (CRD42017079253). Results: Aging greatly influences the outcome of AP. There was a low severe AP incidence in patients under 30 (1.6%); however, the incidence of severe AP showed a continuous, linear increase between 20 and 70 (0.193%/year) of up to 9.6%. The mortality rate was 0.9% in patients under 20 and demonstrated a continuous linear elevation until 59, however from this age the mortality rate started elevating with 9 times higher rate until the age of 70. The mortality rate between 20 and 59 grew 0.086%/year and 0.765%/year between 59 and 70. Overall, patients above 70 had a 19 times higher mortality rate than patients under 20. The mortality rate rising with age was confirmed by meta-regression (coefficient: 0.037 CI: 0.006–0.068, p = 0.022; adjusted r 2 : 13.8%), and severity also (coefficient: 0.035 CI: 0.019–0.052, p < 0.001; adjusted r 2 : 31.6%). Conclusion: Our analysis shows a likelihood of severe pancreatitis, as well as, pancreatitis-associated mortality is more common with advanced age. Importantly, the rapid elevation of mortality above the age of 59 suggests the involvement of additional deteriorating factors such as co-morbidity in elderly.

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Section: Resultsmentioning

confidence: 99%

Aging and Comorbidities in Acute Pancreatitis I: A Meta-Analysis and Systematic Review Based on 194,702 Patients

et al. 2019

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“…En nuestro estudio, encontramos una mortalidad del 1,2%. Estudios similares, encontraron una mortalidad de 2,6%(6), 5,9%(8), 2,1%(10), 3%(11), 4%(12), 6,4%(13) y 5% (15). Esto debido a que, como han avanzado los ajustes en el manejo y tratamiento de la pancrea s, la mortalidad ha ido disminuyendo con el empo; aun así, la causa es por falla mul orgánica, principalmente.…”

Section: Discussionunclassified

Prevalencia, características clínicas y disfunción orgánica según score de Marshall modificado en pacientes con pancreatitis aguda en el Hospital Hipólito Unanue de Tacna 2015 - 2016

Mamani

Rendón

2019

RMB

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OBJETIVO: Determinar la prevalencia, características sociodemográficas, clínicas y disfunción orgánica según Score de Marshall modificado en pacientes con pancreatitis aguda en el servicio de medicina del Hospital Hipólito Unanue de Tacna durante el periodo enero 2015 – diciembre 2016. MATERIAL Y MÉTODOS: Se realizó un estudio descriptivo de tipo transversal – retrospectivo en una población de 161 pacientes. RESULTADOS: La prevalencia fue de 9,26%. El sexo más frecuente fue el femenino (56,5%), la etiología más frecuente fue la biliar (92,6%), la clasificación de la severidad según Atlanta 2012, fue de 73,3%, 20,5% y 6,2% para la categoría leve, moderadamente severa y severa. La prevalencia de disfunción orgánica según Score de Marshall modificado fue de 14,9%, la falla respiratoria se presentó en el 12,4%. La mortalidad fue del 1,2%. CONCLUSIONES: Las mujeres jóvenes y varones adultos tienen mayor frecuencia de presentar pancreatitis aguda, cuya principal causa es la litiasis biliar. A menor severidad del cuadro de pancreatitis aguda, habrá una menor estancia hospitalaria, caso contrario, se requerirá mayor estancia hospitalaria, y si empeora el cuadro, manejo en UCI.

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“…El promedio de la amilasa y lipasa fue de 1594/ul y 1183/ul respectivamente. fue de 6 días (2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17) . Así mismo, en los antecedentes; se evidenciaron 17 pacientes (11,6%) con diabetes mellitus tipo 2 y 5 pacientes (3,4%) presentaron colecistectomía previa a la pancreatitis aguda.…”

Section: Aspectos éTicosunclassified

“…En un estudio realizado en México, se presentó un 80% de pancreatitis leve y una mortalidad de pancreatitis grave de 25 a 30% (4) . En otro trabajo, la etiología biliar fue la más frecuente (66%), seguido de la alcohólica (15%) (5) . Esta descrito que la incidencia varía según el consumo de alcohol y la presencia de litiasis biliar (6) .…”

Section: Introductionunclassified

Comparison of the APACHE II and BISAP scales in the prognosis of acute pancreatitis in a hospital of Peru

García-Revilla¹,

Correa-López

Rubio-Ramos

et al. 2020

RFMH

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Características clínicas de la pancreatitis aguda en México

Abstract: The most frequent AP etiology was biliary, but that caused by alcohol presented with more complications. Overall mortality was 5.00% and was higher in the elderly patients.

Cited by 14 publications

References 36 publications

Aging and Comorbidities in Acute Pancreatitis I: A Meta-Analysis and Systematic Review Based on 194,702 Patients

Aging and Comorbidities in Acute Pancreatitis I: A Meta-Analysis and Systematic Review Based on 194,702 Patients

Prevalencia, características clínicas y disfunción orgánica según score de Marshall modificado en pacientes con pancreatitis aguda en el Hospital Hipólito Unanue de Tacna 2015 - 2016

Comparison of the APACHE II and BISAP scales in the prognosis of acute pancreatitis in a hospital of Peru

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