Goals: The study has been initiated in order to describe the epidemiological, clinical and etiological aspect of the ascites. Patients and methods: This was a retrospective and descriptive study on the patients with an ascite and followed at the medicine department of Borgou departmental teaching hospital. Results: A total of 190 patients have presented an ascite or a hospital prevalence at 3.93%. A male predominance has been observed with a sex-ratio at 1.7. The average age was 39.7 ± 13.9 years. The reason for consultation is dominated by the increase of the abdominal volume (69.5%). The ascite fluid is macroscopically yellow citrine. The cirrhosis (28.5%) and the heart diseases (18.6%) were the most encountered causes of the ascites. Conclusion: The etiologies of ascites are various and dominated by the hepatic cirrhosis and the heart diseases.