Caracterização físico-química e biológica do caule de Caesalpinia ferrea Mart.

Abstract

RESUMO: Visando estabelecer parâmetros para o controle da qualidade do caule de Caesalpinia ferrea Mart. (Caesalpiniaceae), foram realizados testes preconizados pela Farmacopéia Brasileira IV e pela Organização Mundial da Saúde para a avaliação da pureza, através das determinações de materiais estranhos, cinzas totais, cinzas insolúveis em ácido, umidade, ensaios-limites de cloretos e sulfatos, além da pesquisa de contaminantes microbianos no material pulverizado. Para a caracterização dos constituintes, eventualmente presentes na droga vegetal, foram realizadas as determinações de taninos, dos índices de espuma, intumescimento e amargor e o teste de hemólise; também foi realizada a caracterização do extrato etanólico bruto e suas frações por cromatografia em camada delgada.Unitermos: Caesalpinia ferrea; controle de qualidade; drogas vegetais ABSTRACT: Physico-chemical and biological characterization of Caesalpinia ferrea Mart. stems. In order to establish parameters for the control quality of Caesalpinia ferrea Mart. stem, the drug was characterized by the methods described in Farmacopéia Brasileira IV and by the World Health Organization. The powdered plant material was submitted to the following tests for purity evaluation: foreign matter, total ash, acid insoluble ash, water content, chloride and sulfate limit assays, and microbiological contamination. Determination of haemolytic activity, foaming index, swelling index and bitterness index were done to characterize the constituents eventually present in the drug, as well as the characterization of the ethanolic crude extract and its fractions by thinlayer chromatography.

Biosynthesis of silver nanoparticles using Caesalpinia ferrea (Tul.) Martius extract: physicochemical characterization, antifungal activity and cytotoxicity

“…Although the intracellular pathways involved for these biological effects still remain largely unclear, some authors highlight the presence of secondary metabolites, usually flavonoids, tannins and polyphenol compounds, as the cause (Frasson, Bittencourt & Heinzmann, 2003; Carlson et al, 2008; Mittal et al, 2014; Alsahi et al, 2016; Fatimah, 2016). …”

Phenolic Composition and Allelopathy of Libidibia ferrea Mart. ex Tul. in Weeds

“…These results are probably due to a higher availability of the allelochemicals in the solution when infusion extraction is applied since L. ferrea presents a high tannin content (Frasson, Bittencourt, & Heinzmann, 2003), which is more readily solubilized in hot water (Trugillo, Mori, Lima, & Cardoso, 2003). It is important to emphasize the observed differences between infusion and cold extraction, where considering the results of the present study, extract preparation with hot water is widely used with the purpose of obtaining greater extraction especially of plant substances which are less soluble (Ferreira & Áquila, 2000).…”

Quantification of polyphenols and evaluation of antimicrobial, analgesic and anti-inflammatory activities of aqueous and acetone–water extracts of Libidibia ferrea, Parapiptadenia rigida and Psidium guajava

“…L. P. Queiroz belongs to the Caesalpinaceae family and, as a medicinal plant, its use has been reported in the treatment of virus, inflammation and diarrhea (Pereira et al, 2012;de Medeiros et al, 2013;Lopes et al, 2013). Its popular name is ironwood, and it is composed of the following phenolic compounds: condensed tannins, catechins and hydrolysable tannins such as gallic acid and ellagic acid (Frasson et al, 2003;Vasconcelos et al, 2011).…”