Caracterización anatomopatológica de neumonías en cuyes producidas por Streptococcus pneumoniae en crianza intensiva

Abstract

Objetivo. Caracterizar macroscópica y microscópicamente las lesiones causadas por Streptococcus pneumoniae en muestras de pulmón de cuyes (Cavia porcellus) de crianza intensiva de Lima. Materiales y métodos. Se hizo la necropsia de 138 cuyes con signos clínicos de neumonía, y se tomó la muestra de los pulmones afectados. Se realizó el aislamiento bacteriano para la identificación de Streptococcus pneumoniae, utilizando agar sangre y pruebas bioquímicas; se realizó el procesamiento histopatológico utilizando la coloración hematoxilina eosina (HE) de las muestras de tejidos conservados en formol al 10%. Resultados. Del total de los pulmones diagnosticados con neumonía en necropsia, el 17.4 % (24/138) resultó positivo a Streptococcus pneumoniae; De estos, el 75% (18/24) mostró características macroscópicas de neumonía intersticial/Neumonía broncointersticial y 25% (6/24) características macroscópicas de bronconeumonía. En la evaluación microscópica se encontró que el 37.5% presentó tanto para neumonía intersticial y neumonía broncointersticial, y un 25% de ellas corresponden a bronconeumonía. Conclusión. la neumonía intersticial, neumonía broncointersticial y bronconeumonía con diagnóstico de Streptococcus pneumoniae son patrones lesionales encontradas en sistemas de crianza intensiva de Lima.

Characterization of Macroscopic and Microscopic Lesions of the Respiratory System of Guinea Pig (Cavia Porcellus) in Colombian Production Systems

“…additionally, the lung tissue evaluated corresponds to that of small hystricomorph rodents, which can generate greater di culty in its identi cation and therefore, generates that the lesion goes unnoticed at the time of evaluation. These ndings are consistent with those reported in a descriptive study of pneumonia in guinea pigs in Peru by Villanueva-Guzmán 40 . Finally, multifocal granulomatous and embolic pneumonia also presented a higher degree of concordance with respect to microscopic ndings with 14.81% versus 11.04%.…”

“…They mention that, in guinea pig necropsies at their diagnostic center, 65% of animals present some type of respiratory pathology at the time of death, with interstitial pneumonia being the most prevalent nding. Information similar to that reported by Villanueva 40 who report a prevalence of 75% in their study. We share the opinion of the ethological characteristics of the guinea pig, being prey animals, they try to mask clinical signs and disease states 7,36,38 which causes respiratory pathologies in the eld to be underdiagnosed.…”

“…Due to the scarce information regarding the macroscopic and microscopic characterization of respiratory pathologies together with the high presentation of diseases of the respiratory system in guinea pig production systems 40 , the objective of this study is to perform the anatomopathological characterization of the lesions of the nasal cavity, respiratory tract, and lungs of guinea pigs (Cavia porcellus) from traditional and techni ed exploitation systems in the municipality of Pasto.…”