Reactor vessel internal components made of nickel-base alloys are susceptible to environmentally assisted cracking (EAC). A better understanding of the causes and mechanisms of this cracking may permit less conservative estimates of damage accumulation and requirements on inspection intervals. The objective of this work is to evaluate and compare the resistance of Alloys 600 and 690 and their welds, such as Alloys 82, 182, 52, and 152, to EAC in simulated light water reactor environments. The existing crack growth rate (CGR) data for these alloys under cyclic and constant loads have been evaluated to establish the effects of alloy chemistry, cold work, and water chemistry. The experimental fatigue CGRs are compared with CGRs that would be expected in air under the same mechanical loading conditions to obtain a qualitative understanding of the degree and range of conditions for significant environmental enhancement in growth rates. The existing stress corrosion cracking (SCC) data on Alloys 600 and 690 and Alloy 82, 182, and 52 welds have been compiled and analyzed to determine the influence of key parameters on growth rates in simulated PWR and BWR environments. The SCC data for these alloys have been evaluated with correlations developed by Scott and by Ford and Andresen.