Carbon-based designer and programmable fluorescent quantum dots for targeted biological and biomedical applications

Barve, Ketki; Bhatia, Dhiraj; Singh, Umesh Kumar; Yadav, Pankaj

doi:10.1039/d2qm01287a

Cited by 24 publications

(15 citation statements)

References 182 publications

(229 reference statements)

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“…[221][222][223] Nanosized carbon cores containing conjugated p-domains with signicant functional groups produce multicolour uorescence due to the quantum connement effect, one of the main mechanisms among the others. [224][225][226] It is plausible to tweak the characteristic bandgap transition by modifying the size of the p-domains. The increase in the size of the p-domain carbon core causes a smaller bandgap.…”

Section: Quantum Connement Effectmentioning

confidence: 99%

Comprehensive advances in the synthesis, fluorescence mechanism and multifunctional applications of red-emitting carbon nanomaterials

Mandal,

Mishra,

Singh

2023

Nanoscale Adv.

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Section: Quantum Connement Effectmentioning

confidence: 99%

Comprehensive advances in the synthesis, fluorescence mechanism and multifunctional applications of red-emitting carbon nanomaterials

Mandal,

Mishra,

Singh

2023

Nanoscale Adv.

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“…The excitation-dependent emission properties of CDs are previously reported by various mechanisms including quantum confinement effects, surface states and molecular fluorescence, electronegativity of heterogeneous atoms, and massive red edge effects. [41][42][43][44][45][46] The TEM image analysis of this study shows that CDs have similar particle size distributions and do not follow excitation-dependent emission characteristics with respect to size. The FT-IR and XPS spectra confirmed that as the N content increased and the intensity of the -OH peak decreased, the emission wavelength of CDs increased.…”

Section: Pl Emission Mechanismmentioning

confidence: 99%

Synthesis of Multicolor Fluorescent N‐Doped Carbon Dots for Bioimaging Applications

Lee

Kim

2023

Physica Status Solidi (a)

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Carbon dots (CDs) are attracting significant research attention due to their low toxicity and highly favorable photochemical properties. This study reports the synthesis of nitrogen‐doped CDs (N‐CDs) using 3‐aminophenol and o‐phenylenediamine as carbon precursors and their application to nontoxic, biocompatible polychromatic agents for biological imaging studies. The prepared N‐CDs exhibit multicolored fluorescence (blue, green, yellow, orange) with excellent optical stability and biocompatibility. As a result of Fourier‐transform infrared spectroscopy and X‐ray photoelectron spectroscopy, N‐CD is found to have similar –OH and C–H in the surface functional group, showing a graphene structure with good hydrophilicity. The size of the synthesized N‐CDs is confirmed by transmission electron microscopy images to be less than 10 nm. The 3‐4,5‐dimethylthiazol‐2,5‐diphenyl tetrazolium bromide analysis is performed using HeLa cells, and cell survival is very high in all N‐CDs. Among N‐CDs, G‐CDs exhibit the highest fluorescence intensity and provide excellent fluorescence microscopic images for cells in blue, green, and red channels.

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“…Au nanoparticles were toxic at higher concentrations (< 1 μg/ml). [106] Furthermore, size, structure, charge, and surface morphology play crucial roles in the biocompatibility of the nanomaterials. Concentration is another crucial factor.…”

Section: Biocompatibility Of Nanomaterialsmentioning

confidence: 99%

“…The quantum dots showed the lowest toxicity, and carbon nanodots showed the highest toxic effect on all the cell lines and green gram sprouts. Au nanoparticles were toxic at higher concentrations (<1 μg/ml) [106] …”

Section: Biocompatibility Of Nanomaterialsmentioning

confidence: 99%

Plant‐Derived Nanomaterials for Targeted Biological Applications and Smart Agriculture

Ghosh,

Yadav,

Sankaranarayanan

et al. 2023

ChemistrySelect

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Biologically inspired nanomaterials and nanotechnology have advanced in almost all scientific and technological research areas, including biomedical applications and agriculture. Nanomaterials hold immense potential for applications in biomedical and agricultural applications. By harnessing the natural capabilities of plants as sources of reducing and capping agents, the synthesis of nanomaterials becomes cost‐effective eco‐friendly, and yields biocompatible products. Here, we provide a comprehensive overview of various plant‐derived nanomaterials synthesized using different methods, highlighting their applications in biomedical and biological sciences, including bioimaging, biosensing, drug delivery, and therapeutics. Additionally, the impact of nanotechnology on precision agriculture is explored, showcasing recent advancements such as nanofertilizers, nanopesticides, nanobiosensors, and nanocarrier‐mediated delivery systems, which exhibit promising results. These recent developments underscore the transformative potential of nanotechnology in both biomedical and agriculture domains.

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Carbon-based designer and programmable fluorescent quantum dots for targeted biological and biomedical applications

Abstract: Carbon dots (CDs) are emerging nanobiomaterials owing to their exceptional optical and physio-chemical properties. In recent years, they have gained attention due to some of their distinctive applications in biological...

Cited by 24 publications

References 182 publications

Comprehensive advances in the synthesis, fluorescence mechanism and multifunctional applications of red-emitting carbon nanomaterials

Comprehensive advances in the synthesis, fluorescence mechanism and multifunctional applications of red-emitting carbon nanomaterials

Synthesis of Multicolor Fluorescent N‐Doped Carbon Dots for Bioimaging Applications

Plant‐Derived Nanomaterials for Targeted Biological Applications and Smart Agriculture

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