Carbon dots doped tungstic anhydride on graphene oxide nanopanels: A new picomolar-range creatinine selective enzymeless electrochemical sensor

Ponnaiah, Sathish Kumar; Prakash, P.

doi:10.1016/j.msec.2020.111010

Cited by 56 publications

(17 citation statements)

References 76 publications

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“…With this approach, various research groups have demonstrated creatinine detection using a monometallic platform. 24,27 However, in this work, the synergistic effect of Fe-and Cubased binary nanoparticles is explored as their combination may possess better electrochemical performance than the monometallic nanoparticles. 29,30 The second approach of this work is to select a suitable support material for the distribution of binary nanoparticles for better stability and sustainable electrocatalytic activity.…”

Section: T H Imentioning

confidence: 99%

“…Therefore, the development of simple and effective nonenzymatic techniques similar to the clinical diagnosis kits devices for the real-time monitoring of glucose is an important goal for point of care (POC) measurement of creatinine levels. A summary of prior work conducted for nonenzymatic electrochemical detection of creatinine and the gaps in these techniques are shown in Table S1. ,− As mentioned in Table S1, the existing literature reveals that although each exploration involves a unique creatinine detection method, significant gaps still exist. They are as follows: (i) the current responses of the sensors are low in the microamps range and (ii) the lowest and highest creatinine levels in human blood so far reported are out of detection limits.…”

Section: Introductionmentioning

confidence: 99%

“…As creatinine has several donor groups in its main tautomeric form, it can bind with various transition metal ions such as Ag(I), Hg(II), Cd(II), Zn(II), Co(II), Ni(II), Cu(II), Pt(II), and Pd(II) to generate redox currents. With this approach, various research groups have demonstrated creatinine detection using a monometallic platform. , However, in this work, the synergistic effect of Fe- and Cu-based binary nanoparticles is explored as their combination may possess better electrochemical performance than the monometallic nanoparticles. , The second approach of this work is to select a suitable support material for the distribution of binary nanoparticles for better stability and sustainable electrocatalytic activity. Reduced graphene oxide (rGO) meets these requirements as a support material because of its unique physicochemical properties with a high surface area, excellent electrical conductivity, good chemical as well as thermal stability, and low production cost.…”

Section: Introductionmentioning

confidence: 99%

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Facile Detection of Blood Creatinine Using Binary Copper–Iron Oxide and rGO-Based Nanocomposite on 3D Printed Ag-Electrode under POC Settings

Singh

Mandal

Roy

et al. 2021

ACS Biomater. Sci. Eng.

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Metal nanoparticles have been helpful in creatinine sensing technology under point-of-care (POC) settings because of their excellent electrocatalyst properties. However, the behavior of monometallic nanoparticles as electrochemical creatinine sensors showed limitations concerning the current density in the mA/cm2 range and wide detection window, which are essential parameters for the development of a sensor for POC applications. Herein, we report a new sensor, a reduced graphene oxide stabilized binary copper–iron oxide-based nanocomposite on a 3D printed Ag-electrode (Fe–Cu–rGO@Ag) for detecting a wide range of blood creatinine (0.01 to 1000 μM; detection limit 10 nM) in an electrochemical chip with a current density ranging between 0.185 and 1.371 mA/cm2 and sensitivity limit of 1.1 μA μM–1 cm–2 at physiological pH. Interference studies confirmed that the sensor exhibited no interference from analytes like uric acid, urea, dopamine, and glutathione. The sensor response was also evaluated to detect creatinine in human blood samples with high accuracy in less than a minute. The sensing mechanism suggested that the synergistic effects of Cu and iron oxide nanoparticles played an essential role in the efficient sensing where Fe atoms act as active sites for creatinine oxidation through the secondary amine nitrogen, and Cu nanoparticles acted as an excellent electron-transfer mediator through rGO. The rapid sensor fabrication procedure, mA/cm2 peak current density, a wide range of detection limits, low contact resistance including high selectivity, excellent linear response (R 2 = 0.991), and reusability ensured the application of advanced electrochemical sensor toward the POC creatinine detection.

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Section: T H Imentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Facile Detection of Blood Creatinine Using Binary Copper–Iron Oxide and rGO-Based Nanocomposite on 3D Printed Ag-Electrode under POC Settings

Singh

Mandal

Roy

et al. 2021

ACS Biomater. Sci. Eng.

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“…Um aglomerado de materiais como, os pontos quânticos, podem agir como armadilhas de elétrons. Emissão de fluorescência neles ocorre quando elétrons excitados caem para um nível mais baixo de energia presente em sua estrutura (FANG et al, 2020;MOLAEI, 2019;PONNAIAH;PRAKASH, 2020). Essas estruturas possuem forte relação entre o comprimento da onda da radiação eletromagnética absorvida e emitida, como tamanho das nanoestruturas.…”

Section: Pontos Quânticosunclassified

A Importância Do Trabalho Experimental No Processo Ensino- Aprendizagem Na Educação De Jovens E Adultos

Manuel¹,

Frutuoso²

2021

A Geração De Novos Conhecimentos Na Química

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Direitos para esta edição cedidos à Atena Editora pelos autores. Todo o conteúdo deste livro está licenciado sob uma Licença de Atribuição Creative Commons. Atribuição-Não-Comercial-NãoDerivativos 4.0 Internacional (CC BY-NC-ND 4.0).O conteúdo dos artigos e seus dados em sua forma, correção e confiabilidade são de responsabilidade exclusiva dos autores, inclusive não representam necessariamente a posição oficial da Atena Editora. Permitido o download da obra e o compartilhamento desde que sejam atribuídos créditos aos autores, mas sem a possibilidade de alterá-la de nenhuma forma ou utilizá-la para fins comerciais. Todos os manuscritos foram previamente submetidos à avaliação cega pelos pares, membros do Conselho Editorial desta Editora, tendo sido aprovados para a publicação com base em critérios de neutralidade e imparcialidade acadêmica.A Atena Editora é comprometida em garantir a integridade editorial em todas as etapas do processo de publicação, evitando plágio, dados ou resultados fraudulentos e impedindo que interesses financeiros comprometam os padrões éticos da publicação. Situações suspeitas de má conduta científica serão investigadas sob o mais alto padrão de rigor acadêmico e ético.

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“…[3,4] Over the years, researchers develop more advanced techniques to improve the traditional approaches. It mainly involves the usage of high-end instruments such as gas chromatographymass spectrometry (GC-MS), [5] electrochemical, [6,7] LC-MS [8] and microfluidics [9] techniques. However, the approaches above suffer from invasiveness, complication fabrication steps, expensive and unable to be used for point of care testing.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of a 1,4‐Bis[2‐(5‐thiophen‐2‐yl)‐1‐benzothiophene]‐2,5‐dioctyloxybenzene Pentamer for Creatinine Detection

et al. 2021

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The synthesis of novel material 1,4‐bis[2‐(5‐thiophen‐2‐yl)‐1‐benzothiophene]‐2,5‐dioctyloxybenzene pentamer (BOBzBT2) was carried out via Williamson etherification, bromination, and Suzuki coupling. Functionalization was carried out via the incorporation of dioctyloxy‐substituents on phenylene moiety to improve its solubility. The elongation of the π‐conjugation backbone was carried out through the addition of benzo[b]thiophene rings of BOBzBT2 to accelerate cation radicals′ formation. In FTIR, the disappearance of the stretching peak of υ(CBr) at 657 cm−1 confirms the coupling of benzo[b]thiophene rings end‐capped the BOBzBT2 UV‐visible shows the appearance of two broad bands at 343 nm and 422 nm, that related to π‐π* transition between thiophene and bithiophene groups with 2,5‐bis(dioctyloxy)benzene moiety in the π‐conjugated backbone, respectively. DSC shows that the BOBzBT2 is a high purity compound. A gradual relaxation occurred between BOBzBT2 with creatinine as observed in UV‐visible analysis. It is expected that the BOBzBT2 sensed creatinine via NH−S and NH−O hydrogen bonding interactions.

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Carbon dots doped tungstic anhydride on graphene oxide nanopanels: A new picomolar-range creatinine selective enzymeless electrochemical sensor

Cited by 56 publications

References 76 publications

Facile Detection of Blood Creatinine Using Binary Copper–Iron Oxide and rGO-Based Nanocomposite on 3D Printed Ag-Electrode under POC Settings

Facile Detection of Blood Creatinine Using Binary Copper–Iron Oxide and rGO-Based Nanocomposite on 3D Printed Ag-Electrode under POC Settings

A Importância Do Trabalho Experimental No Processo Ensino- Aprendizagem Na Educação De Jovens E Adultos

Synthesis of a 1,4‐Bis[2‐(5‐thiophen‐2‐yl)‐1‐benzothiophene]‐2,5‐dioctyloxybenzene Pentamer for Creatinine Detection

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