“… Property NRFX Appearance CAS ID crystalline powder (white to light-yellow) 70,458–96–7 IUPAC Name 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid Chemical Formula Composition (%) C (60.18), H (5.68), F (5.95), N (13.16), O (15.03) Molecular weight (g/mol) 319.33 Exact molar mass (g/mol) 319.13321961 Polar surface area (Å 2 ) 72.9 Water Solubility (at 25 °C, pH = 7) 400 mg/L λ max /nm 278 pKa (Dual) 6.22 and 8.51 Heavy atom count 23 Molecular dimensions, size (Å) L12.2 Å ×W8.2 Å ×H7.0 Å 1.03 H 2 bond count (Donor) 2 H 2 bond count (Acceptor) 7 Melting point 220 – 221 °C Fig. 1 Chemical structure of NRFX (Adopted from [2] ). …”
Section: Ecotoxicology Of Nrfxmentioning
confidence: 99%
“…These include pharmaceutical compounds, illicit drugs, surfactants, etc. [ 1 , 2 ]. Antibiotics are the most significant and widely detected ECs because they are the third most widely used drugs in contemporary medicine, reportedly, above six percent of general prescription drugs [3] .…”
Section: Introductionmentioning
confidence: 99%
“…Indiscriminate discharge of these drugs has increased their presence in the environment, with a consequential impact on aquatic life, triggering changes in their growth and survival [ 4 , 5 ]. In addition, they also aid bacterial resistance, posing serious human health and environmental concerns [ 2 , 6 ].…”
Section: Introductionmentioning
confidence: 99%
“…Norfloxacin (NRFX) is a class of fluoroquinolone antibiotic commonly employed to combat both Gram-positive and Gram-negative bacteria [ 2 , 7 , 8 ]. NRFX has been broadly used as human medication (typically for the treatment of prostatitis and urinary tract infections) and veterinary medicine [9] .…”
“… Property NRFX Appearance CAS ID crystalline powder (white to light-yellow) 70,458–96–7 IUPAC Name 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid Chemical Formula Composition (%) C (60.18), H (5.68), F (5.95), N (13.16), O (15.03) Molecular weight (g/mol) 319.33 Exact molar mass (g/mol) 319.13321961 Polar surface area (Å 2 ) 72.9 Water Solubility (at 25 °C, pH = 7) 400 mg/L λ max /nm 278 pKa (Dual) 6.22 and 8.51 Heavy atom count 23 Molecular dimensions, size (Å) L12.2 Å ×W8.2 Å ×H7.0 Å 1.03 H 2 bond count (Donor) 2 H 2 bond count (Acceptor) 7 Melting point 220 – 221 °C Fig. 1 Chemical structure of NRFX (Adopted from [2] ). …”
Section: Ecotoxicology Of Nrfxmentioning
confidence: 99%
“…These include pharmaceutical compounds, illicit drugs, surfactants, etc. [ 1 , 2 ]. Antibiotics are the most significant and widely detected ECs because they are the third most widely used drugs in contemporary medicine, reportedly, above six percent of general prescription drugs [3] .…”
Section: Introductionmentioning
confidence: 99%
“…Indiscriminate discharge of these drugs has increased their presence in the environment, with a consequential impact on aquatic life, triggering changes in their growth and survival [ 4 , 5 ]. In addition, they also aid bacterial resistance, posing serious human health and environmental concerns [ 2 , 6 ].…”
Section: Introductionmentioning
confidence: 99%
“…Norfloxacin (NRFX) is a class of fluoroquinolone antibiotic commonly employed to combat both Gram-positive and Gram-negative bacteria [ 2 , 7 , 8 ]. NRFX has been broadly used as human medication (typically for the treatment of prostatitis and urinary tract infections) and veterinary medicine [9] .…”
“…In this study, montmorillonite-carbon nanocomposites (M-HC) were produced by hydrothermal carbonization of carbohydrates in presence of M sample. In a previous work, authors reported that similar M-HC materials showed higher reutilization capacity than that of M for norfloxacin (NOR) sorption (Zelaya Soulé et al, 2019).…”
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