“…These concentra-tions, as well as the gender related differences in concentration among never smokers in Norway, are in agreement with previous observations in a large population of nonsmoking blood donors in St Louis, Missouri. 26 The variation among subjects may be due to differences in concentration of carbon monoxide in the inspired air, endogenous carbon monoxide production, and exercise level. A multiple linear regression which included height, age, and haemoglobin concentration showed that the decrease in TLCO with increasing carboxyhaemoglobin concentration was of borderline significance in women and was not significant in men (table 4).…”