Carboxymethylcellulose Supported Cinchonine as a Recyclable Catalyst for Asymmetric Michael Reaction

Enantioselective Michael addition of aldehydes to maleimides catalysed by surface-adsorbed natural amino acids

“…However, most of the latter were obtained by covalent bonding of the optically pure organocatalysts to insoluble supports, which needed several, sometimes synthetically demanding, preparation steps. [52][53][54][55][56][57][58][59][60] Only in few procedures was covalent immobilization of the catalytic materials avoided. Thus, optically pure hyperbranched polymers worked in a synergistic way with quinine to afford succinimides with moderate enantioselectivities.…”