Carcinóide Pulmonar: Análise de Experiência Institucional e Fatores Prognóstico

Correia, Sílvia; Pinto, Carlos Eduardo Pinto de; Bernardo, João

doi:10.20344/amp.5390

Cited by 4 publications

(1 citation statement)

References 18 publications

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“…Lung carcinoid tumors are rare tumors originating in lung neuroendocrine cells. 1 Although infrequent, their incidence has been increasing in the recent decades, 2 currently 2 per 100 000 inhabitants. 3 About 30% are functionally active due to the release of biogenic amines into the bloodstream, giving rise to carcinoid syndrome.…”

Section: Introductionmentioning

confidence: 99%

Psicose Orgânica em Doente com Tumor Carcinoide Atípico do Pulmão

Gomes

Santos

Moutinho

et al. 2022

RPPSM

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Manifestações psiquiátricas estão presentes em pelo menos um terço dos doentes com cancro. Apesar disso, menos de 50% são devidamente acompanhados. Este artigo contribui para a escassa literatura existente sobre sintomas psicóticos em doentes com tumores neuroendócrinos ‐ uma apresentação rara de uma doença rara. Enfatiza uma possível associação entre tumor carcinoide do pulmão e sintomas psicóticos, discute o diagnóstico diferencial e apresenta uma opção terapêutica psicofarmacológica eficaz, nunca publicada, até onde sabemos. Relatamos o caso de uma doente de 69 anos com um tumor carcinoide atípico do pulmão, sem história psiquiátrica prévia. O quadro clínico caracterizou‐se por ideias delirantes paranoides e autoreferenciais, atividade alucinatória acústico‐verbal, humor depressivo e ansiedade extrema secundários. Foi admitida uma psicose orgânica em provável relação com a sua doença neoplásica, que foi tratada com aripiprazol, com boa resposta e tolerância.

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Section: Introductionmentioning

confidence: 99%

Psicose Orgânica em Doente com Tumor Carcinoide Atípico do Pulmão

Gomes

Santos

Moutinho

et al. 2022

RPPSM

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Bronchoplasty for the treatment of carcinoid tumour

Zribi

Ayed

Abdelkbir

et al. 2020

Respirology Case Reports

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Lung carcinoid tumours are rare neoplasms with a favourable prognosis. Bronchoplasty can be a conservative treatment for typical carcinoid tumours and can be applied for patients with limited respiratory function. We report the case of a 34‐year‐old woman, with a polypoid tumour located at the distal right main bronchus. Bronchial biopsy showed a typical carcinoid tumour. After resection of the tumour in the right main bronchus, bronchoplasty was performed by end‐to‐end anastomosis of the remaining right main bronchus, right upper lobar bronchus, and the upper bronchus intermedius. Bronchoscopy showed a good quality anastomosis with slightly reduced endoluminal calibre only. The post‐operative period was uneventful and the patient was discharged at the seventh day. One year later, no complications occurred and the patient is still being followed up regularly.

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Natural History of Localized and Locally Advanced Atypical Lung Carcinoids after Complete Resection: A Joined French-Italian Retrospective Multicenter Study

Marciello

Mercier

Ferollà³

et al. 2017

Neuroendocrinology

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Background: The natural history and the best modality of follow-up of atypical lung carcinoids (AC) remain ill defined. The aim of this study was to analyze recurrence-free survival (RFS) after complete resection (R0) of stage I-III pulmonary AC. Secondary objectives were prognostic parameters, the location of recurrences, and the modality of follow-up. Methods: A retrospective review of 540 charts of AC patients treated between 1998 and 2008 at 10 French and Italian centers with experience in lung neuroendocrine tumor management was undertaken. The exclusion criteria were MEN1-related tumor, history of another cancer, referral after tumor relapse, and being lost to follow-up. A central pathological review was performed in each country. Results: Sixty-two patients were included. After a median follow-up time of 91 months (mean 85, range 6-165), 35% of the patients experienced recurrence: 16% were regional recurrences and 19% were distant metastases. Median RFS was not reached. The 1-, 3-, and 5-year RFS rate was 90, 79, and 68%, respectively. In univariate analysis, lymph node involvement (p = 0.0001), stage (p = 0.0001), mitotic count (p = 0.004), and type of surgery (p = 0.043) were significantly associated with RFS. In multivariate analysis, lymph node involvement was significantly associated with RFS (HR 95% CI: 0.000-0.151; p = 0.004). During follow-up, somatostatin receptor scintigraphy, fibroscopy, and abdominal examination results were available for 22, 12, and 25 patients, respectively. The median time interval for imaging follow-up was 10 months. Conclusions: After complete resection of AC, recurrences were observed mostly within the first 5 years of follow-up, within bronchi, mediastinal nodes, the liver, and bones. In R0 patients, lymph node involvement could help to stratify follow-up intervals. Suboptimal imaging is evidenced.

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Carcinóide Pulmonar: Análise de Experiência Institucional e Fatores Prognóstico

Cited by 4 publications

References 18 publications

Psicose Orgânica em Doente com Tumor Carcinoide Atípico do Pulmão

Psicose Orgânica em Doente com Tumor Carcinoide Atípico do Pulmão

Bronchoplasty for the treatment of carcinoid tumour

Natural History of Localized and Locally Advanced Atypical Lung Carcinoids after Complete Resection: A Joined French-Italian Retrospective Multicenter Study

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